Results 181 to 190 of about 11,498,837 (391)

Long non‑coding RNA HOTAIR overexpression improves premature ovarian failure by upregulating Notch‑1 expression

, 2018
Wei Zhao, Liwei Dong
openalex   +2 more sources

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Nuclear medicine in the management of patients with heart failure

, 2014
Amalia Peix, Cláudio Tinoco Mesquita, Diana Páez, Carlos Cunha Pereira, R Felix, Claudia Gutiérrez, Rodrigo Jaimovich, Bárbara Maria Ianni, José Soares, Pastor Olaya, Ma. Victoria Rodriguez, Albert Flotats, Raffaele Giubbini, Mark I. Travin, Ernest Garcia   +14 more
openalex   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Power failure: why small sample size undermines the reliability of neuroscience

Nature Reviews Neuroscience, 2013
K. Button, J. Ioannidis, C. Mokrysz, Brian A. Nosek, J. Flint, E. Robinson, M. Munafo   +6 more
semanticscholar   +1 more source

Peak oxygen uptake and left ventricular ejection fraction, but not depressive symptoms, are associated with cognitive impairment in patients with chronic heart failure

, 2011
Jana Juenger, LOSSNITZER, Schellberg, Mueller-Tasch, Krueger, Haass, Ladwig, Herzog, Jana Juenger, Gerrit Steinberg   +9 more
openalex   +2 more sources

Role of Echocardiography in Evaluation of the Effects of Sacubitril–Valsartan on Vascular Stiffness in Patients with Heart Failure: Review Article [PDF]

, 2022
Elshaimaa Ali Elsadek Seaoud, Tarek Ahmad Naguib, Ismail Talha Elbarky, Moataz Abdelmonem Elkot   +3 more
openalex   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Wearable Sensors to Monitor Physical Activity in Heart Failure Clinical Trials: State-of-the-Art Review [PDF]

Rubén Buendía, Martin Karpefors, Folke Folkvaljon, ROBERT HUNTER, Henrik Sillén, Long Luu, Kieran F. Docherty, Martín Cowie   +7 more
openalex   +1 more source

Heart Failure with Preserved Ejection Fraction Induced Reactive Pulmonary Hypertension Lacks Nitric Oxide Vasoreactivity Similar to Pulmonary Arterial Hypertension [PDF]

, 2014
Jason N. Salamon, Jeremy A. Mazurek, R. Zolty   +2 more
openalex   +1 more source