Results 41 to 50 of about 5,959,491 (252)

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Brachial pulse pressure in acute heart failure. Results of the Heart Failure Registry [PDF]

, 2019
[Abstract] Aims To investigate the still uncertain independent prognostic impact of pulse pressure (PP) in acute heart failure (HF), in particular across the left ventricular ejection fraction (EF) phenotypes, and the potential contribution of PP in ...
Macarie, Cezar,, Laroche, Cécile, Bonapace, Stefano,, Maggioni, Aldo P.,, Crespo-Leiro, Maria G., Ulf Dahlström, Maggioni, Aldo P, Andrea Rossi, Piepoli, Massimo F.,, Andrew J.S. Coats, Pier Luigi Temporelli, Maria G. Crespo‐Leiro, Malek, Filip, Tavazzi, Luigi,, Temporelli, Pier Luigi, Crespo-Leiro, María Generosa, Rossi, Andrea,, Rossi, Andrea, Stefano Bonapace, Cécile Laroche, Crespo-Leiro, Maria G.,, Bonapace, Stefano, Malek, Filip,, Dahlström, Ulf, Temporelli, Pier Luigi,, Coats, Andrew J S, Massimo F. Piepoli, Piepoli, Massimo F, Macarie, Cezar, Coats, Andrew J. S.,, Coats, Andrew J. S., Laroche, Cecile,, Filip Malek, Crespo Leiro, Marisa, Cezar Macarie, Luigi Tavazzi, Maggioni, Aldo P., Dahlström, Ulf,, Tavazzi, Luigi, Aldo P. Maggioni, Piepoli, Massimo F.   +40 more
core   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

The Effects of Failure Types on Cold Forging Dies

Journal of Advances in Manufacturing Engineering, 2021
Fastener preferences are also changing in parallel with the development of the automotive industry. During these periods, when light-weightings and carbon emissions have great importance; each part used is forced to be lighter, carbon footprints are ...
Talha Çakmak, Şevki Alp Adaçağlar
doaj  

Effects of cell aspect ratio and relative density on deformation response and failure of honeycomb core structure

Materials Research Express, 2020
The extensive applications of honeycomb (HC) core in sandwich structures necessitates the influence of the cellular geometry and cell wall base material on the mechanical response to be quantified. In this respect, this paper establishes the mechanics of
Muhammad Salman Khan, Seyed Saeid Rahimian Koloor, Mohd Nasir Tamin   +2 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

The Progressive Development and Post-failure Behaviour of Deep-seated Landslide Complexes [PDF]

, 2011
The concept of progressive shear surface development remains to be fully understood. This study aims to investigate the mechanisms of progressive shear surface development to failure, and the subsequent post-failure behaviour, of deep-seated landslide ...
CAREY, JONATHAN,MARTIN, Carey, Jonathan Martin   +1 more
core  

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source