Results 91 to 100 of about 1,659,508 (308)

Accelerated fatigue durability of a high performance composite [PDF]

The fatigue behavior of multidirectional graphite-epoxy laminates was analyzed theoretically and experimentally in an effort to establish an accelerated testing methodology.
Rotem, A.
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Failure Mode Analysis of Engine Timing System

Jixie chuandong, 2016
The failure modes of the timing system are classified,the internal factors and the external environment factors are distinguished in detail. Combining the failure summary of failure of 78 kits of failure timing system,the parts with the highest frequency
Xing Jianheng, Lu Xudong, Xu Bin, Wang Hongjun   +3 more
doaj  

Recognition of Failure Mode of Slope Block Failure Mode in Zhouning Pumped Storage Station Based on Stereographic Projection Method

Renmin Zhujiang, 2020
Deformation and failure of rock slope are mainly controlled by structural planes developed in rock mass. The stereographic projection method is used to analyze the failure modes of rock slope, which can easily determine the combination relationship ...
KANG Zhiliang, ZHOU Shuntian, ZHU Yongsheng, CHU Weijiang, PAN Bing   +4 more
doaj  

Procedure for Failure Mode, Effects, and Criticality Analysis (FMECA) [PDF]

This document provides guidelines for the accomplishment of Failure Mode, Effects, and Criticality Analysis (FMECA) on the Apollo program. It is a procedure for analysis of hardware items to determine those items contributing most to system unreliability

core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Investigation of the mechanical behavior of rock-like material with two flaws subjected to biaxial compression

Scientific Reports
The biaxial compression experiments of rock-like materials with two flaws are carried out under different flaw inclination angle, rock bridge ligament angle, lateral stress. The experimental studies show that crack propagation modes of rock-like material
Shuailong Lian, Wen Wan, Yanlin Zhao, Qiuhong Wu, Can Du   +4 more
doaj   +1 more source

Fracturing Process Visualization of Cracked Chevron-Notched Brazilian Discal and Notch Semicircular Bend Rock Specimens and Comparative Analysis by Combined AE and DIC [PDF]

Lithosphere
A series of homogeneous granite specimens were prepared to investigate the Mode I fracture toughness (K_IC) using the cracked chevron-notched Brazilian disk (CCNBD) method and semicircular three-point bending (NSCB) method recommended by the ...
Peng Sha, You Lv, Jiacong Chen
doaj   +1 more source

GEOS A telemetry subsystem reliability assessment Technical advisement memorandum no. 106-11 [PDF]

Geodetic satellite telemetry subsystem performance prediction based on failure mode and effects ...
Bloomquist, C. E., Graham, W. C.
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source