Results 71 to 80 of about 4,249,486 (246)
International Journal of Lightweight Materials and Manufacture, 2019 In this work, the numerical and experimental study was performed to explore the mechanical properties and failure behavior of steel-aluminium mechanical clinched joints under multiple test conditions.
Yanli Song +4 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Failure mode analysis on concentrated solar power (CSP) plants : a case study on solar tower power plant [PDF]
, 2016 This thesis is an investigation of critical failure modes of solar tower power system in concentrated solar power (CSP) technology. The thesis evaluated the causes and impacts of failure on the major components and apply the failure Mode and Effect ...
Avapak, Sukunta
core +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Chengshi guidao jiaotong yanjiuObjective Under the DRB (driverless return button) mode on Xi’an Metro Line 14, the train emergency braking will occur after the train automatically switching its head car on the turn-back line, resulting in the train turn-back failure.
FANG Jiewei
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Numerical methodology for analyses of tubular KK multiplanar steel joints
REM: International Engineering JournalHerein is presented a numerical methodology for a static resistance analysis of symmetrically loaded multiplanar KK joints in circular hollow steel sections.
Nádia Cazarim da Silva Forti +2 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Governing failure mode of unsaturated soil slopes under rainwater infiltration
E3S Web of Conferences, 2016 Due to rainwater infiltration and loss of matric suction above the wetting font, both translational and rotational slips may occur in an unsaturated soil slope. It is useful to know which failure mode is more critical.
Huang Wengui +2 more
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source