Results 31 to 40 of about 395,957 (267)
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier +11 more
wiley +1 more source
Determining Parental Factors for Clinical Trial Attrition in Pediatric Acute Lymphoblastic Leukemia
ABSTRACT Background/Objectives Despite high enrollment rates on Children's Oncology Group (COG) protocols, attrition after initial consent is challenging, introducing bias and prolonging trial completion. While adult oncology literature has identified predictors of withdrawal, little is known about caregiver decision‐making for child participation in ...
Kimberly L. Stathas +3 more
wiley +1 more source
An experimental study of a rock-like material containing a preexisting fissure subjected to loading and unloading triaxial compression is carried out, and the results show that the mechanical characteristics of the rock-like specimen depend heavily on ...
Taoli Xiao, Mei Huang, Min Gao
doaj +1 more source
Sea ice is composed of columnar-shaped grains. To investigate the influence of the loading direction on the uniaxial compressive strength and failure processes of sea ice, field experiments were performed with first-year level ice.
Shunying Ji, Xiaodong Chen, Anliang Wang
doaj +1 more source
Application of PFMA in safety monitoring of concrete face rockfill dams
With the development of dam risk management concept, potential failure mode analysis (PFMA) method is becoming more and more widely used. The design of dam safety monitoring based on traditional engineering safety concept lacks pertinence to hidden ...
FENG Longhai +3 more
doaj +1 more source
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono +7 more
wiley +1 more source
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
An Experimental Study on Mechanical Behavior of Parallel Joint Specimens under Compression Shear
In order to investigate the influence of the joint on the failure mode, peak shear strength, and shear stress-strain curve of rock mass, the compression shear test loading on the parallel jointed specimens was carried out, and the acoustic emission ...
Fei Wang +4 more
doaj +1 more source
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin +2 more
wiley +1 more source
Landslide susceptibility mapping based on triggering factors using a multi-modal approach [PDF]
Landslide susceptibility mapping has been done using statistical and physically-based assessment techniques with limited focus on mode-specific models to identify failure modes and runout patterns. Because each failure mode has different consequences, it
Kaafarani Rouba +3 more
doaj +1 more source

