Results 41 to 50 of about 1,598 (214)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FMEA (FAILURE MODE AND EFFECTS ANALYSIS) AND PROPOSAL OF RISK MINIMIZING IN STORAGE PROCESSES FOR AUTOMOTIVECLIENT [PDF]
Acta Logistica, 2016 There are several quality tools that support achievement of goals and ensure primary basis for promoting quality in enterprises. FMEA is a quantitative inductive method, which was created for the recognizing and evaluating of products ...
Kristína Ignáczová
doaj +1 more source
Security Application of Failure Mode and Effect Analysis (FMEA) [PDF]
, 2014 Increasingly complex systems lead to an interweaving of security, safety, availability and reliability concerns. Most dependability analysis techniques do not include security aspects. In order to include security, a holistic risk model for systems is needed.
Christoph Schmittner +3 more
openaire +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Engineering ProceedingsCompetition in the industry forces palm oil producers to keep raising the caliber of their output. One of the businesses involved in the Crude Palm Oil sector is PT. XYZ. The quality of the CPO that PT. XYZ produces is a top priority.
Nismah Panjaitan +3 more
doaj +1 more source
Failure Mode and Effect Analysis of Subsea Multiphase Pump Equipment
MATEC Web of Conferences, 2014 Finding oil and gas reserves in deep/harsh environment with challenging reservoir and field conditions, subsea multiphase pumping benefits has found its way to provide solutions to these issues.
Oluwatoyin Shobowale Kafayat +2 more
doaj +1 more source
Using the Failure Mode and Effect Analysis Tool to Improve the Automatic Stop Order Process [PDF]
Global Journal on Quality and Safety in HealthcareIntroduction Automatic stop orders (ASOs) in computerized prescription order entry (CPOE) systems predefine the length of treatment. This can improve resource use for select therapies (e.g., empirical antibiotics).
Ghada Hussain Al Mardawi +3 more
doaj +1 more source