Results 61 to 70 of about 296,075 (303)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Failure Mode and Effect Analysis of Subsea Multiphase Pump Equipment

open access: yesMATEC Web of Conferences, 2014
Finding oil and gas reserves in deep/harsh environment with challenging reservoir and field conditions, subsea multiphase pumping benefits has found its way to provide solutions to these issues.
Oluwatoyin Shobowale Kafayat   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Risk Identification and Risk Assessment Using Failure Mode and Effect Analysis in a Textile Industry

open access: yesCaspian Journal of Health Research, 2019
Background: Today with growth of industry, occupational hazards are increasing proportionally. One of the most important parts of these industries are human resources, which face with many various hazards.
Atefe Mohamadinejad   +5 more
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Intensive Care Unit Risk Assessment: A Systematic Review

open access: yesIranian Journal of Public Health, 2020
Background: It is of paramount importance to reduce the probability of clinical risks to improve the quality of health care services, make the relationship between service providers and patients more effective, enhance patient satisfaction, and decrease ...
Abbas HOMAUNI   +3 more
doaj   +1 more source

Food Safety Risk Analysis of Songkem Duck Using Failure Mode and Effect Analysis (FMEA) Method

open access: yesPROZIMA (Productivity Optimization and Manufacturing System Engineering)
Food safety is an essential aspect of human health. Food processed without paying attention to food safety regulations can harm consumer health. This research aims to 1) identify activities with food safety risks, 2) determine the sequence of food safety
Mawadatun Anisa   +2 more
semanticscholar   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Peningkatan Pengendalian Kualitas Produk Roti dengan Penerapan Metode FMEA (Failure Mode and Effect Analysis) dan FTA (Fault Tree Analysis) di Home Industry

open access: yesNusantara Technology and Engineering Review
Penelitian ini bertujuan untuk mengetahui jenis cacat, penyebabnya dan juga memberikan solusi yang tepat untuk menekan angka kecacatan produksi. Metodologi yang digunakan adalah menggunakan failure mode and effect analysis (FMEA) untuk mengetahui jenis ...
M. Afiyanto, Untung Usada
semanticscholar   +1 more source

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