Results 81 to 90 of about 289,433 (344)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Marine engineering systems have a fundamental role in ensuring the efficiency, safety, and sustainability of maritime transportation. The performance and reliability of these systems, particularly propulsion systems, are of paramount importance.
Sengül, Dogan +2 more
core +2 more sources
Risk Identification and Risk Assessment Using Failure Mode and Effect Analysis in a Textile Industry
Caspian Journal of Health Research, 2019 Background: Today with growth of industry, occupational hazards are increasing proportionally. One of the most important parts of these industries are human resources, which face with many various hazards.
Atefe Mohamadinejad +5 more
doaj
The Reliability of a Tunnel Boring Machine [PDF]
Greater levels of complexity in tunnelling with Tunnel Boring Machine (TBM) allow higher chances of fail-ures that may increase the potential hazardous risks. This paper presents the results of a study on TBM reliability using risk analysis.
جعفری, محمدجواد +1 more
core
Damage and strain rate optical characterisation of standard and tufted non crimp fabric carbon composites for Meso-scale impact models [PDF]
, 2009 As global warming is a prime concern to the wellbeing of the planet, lighter planes are a requirement to reduce CO2 emissions. Light structures made of carbon epoxy composite materials are of particular interest but are sensitive to impacts such as
Colin de Verdiere, Mathieu
core
, 2011 With the publication of the quality guideline ICH Q9 "Quality Risk Management" by the International Conference on Harmonization, risk management has already become a standard requirement during the life cycle of a pharmaceutical product. Failure mode and
Hentschel, Norbert +1 more
core +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Failure mode effect and analysis
, 2011 katedra: KVS; rozsah: 63 s.This diploma wok concerns with failure mode effect and analysis. Subject those work is general process of production pressure die casting, which si in those work detailed semiquantification classification potential ...
Hollósiová, Šárka
core
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source