Evaluating the academic scientific laboratories' safety by applying failure mode and effect analysis (FMEA) at the public university in Lebanon. [PDF]
Heliyon, 2023 Nasrallah I +8 more
europepmc +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Identification of priorities for medication safety in the neonatal intensive care unit via failure mode and effect analysis [PDF]
Iranian Journal of Neonatology, 2016 Prevention of medication errors in neonatal intensive care units (NICUs) is of paramount importance due to age-specific and physiological conditions of neonates.
Ali Vafaee Najar +4 more
doaj
Failure mode and Effect Analysis of personal fall arrest system under the intuitionistic fuzzy environment. [PDF]
Heliyon, 2023 Ghasemi F, Rahimi J.
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Advanced approaches to failure mode and effect analysis (FMEA) applications
Metalurgija, 2015 The present paper explores advanced approaches to the FMEA method (Failure Mode and Effect Analysis) which take into account the costs associated with occurrence of failures during the manufacture of a product. Different approaches are demonstrated using
D. Vykydal +3 more
doaj
Healthcare Failure Mode and Effect Analysis in Surgery Setting: A Bibliometrics Analysis and Literature Review. [PDF]
Acta Inform Med, 2023 Sumarwoto T, Ilyas MF, Dewi A.
europepmc +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Mitigating the risk of COVID-19 infection in the operating room: Using healthcare failure mode and effect analysis. [PDF]
Perioper Care Oper Room Manag, 2023 Meziane S, Taous M, Bourkhiss B.
europepmc +1 more source