Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Identification of priorities for medication safety in the neonatal intensive care unit via failure mode and effect analysis [PDF]
Iranian Journal of Neonatology, 2016 Prevention of medication errors in neonatal intensive care units (NICUs) is of paramount importance due to age-specific and physiological conditions of neonates.
Ali Vafaee Najar +4 more
doaj
Mitigating the risk of COVID-19 infection in the operating room: Using healthcare failure mode and effect analysis. [PDF]
Perioper Care Oper Room Manag, 2023 Meziane S, Taous M, Bourkhiss B.
europepmc +1 more source
Cost consequence of failure in failure mode and effect analysis
, 2017 Purpose The purpose of this paper is to investigate the possibility of including the cost consequence of failure in the a priori risk assessment methodology known as failure mode and effect analysis (FMEA).
Jeffrey M. Ulmer +3 more
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Healthcare Failure Mode and Effect Analysis in Surgery Setting: A Bibliometrics Analysis and Literature Review. [PDF]
Acta Inform Med, 2023 Sumarwoto T, Ilyas MF, Dewi A.
europepmc +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Advanced approaches to failure mode and effect analysis (FMEA) applications
Metalurgija, 2015 The present paper explores advanced approaches to the FMEA method (Failure Mode and Effect Analysis) which take into account the costs associated with occurrence of failures during the manufacture of a product. Different approaches are demonstrated using
D. Vykydal +3 more
doaj
Fall risk management in interventional prenatal diagnosis perioperative pregnant women based on tracking methodology and failure mode and effect analysis application. [PDF]
Medicine (Baltimore), 2023 Yang H, Luo W, Guo L, Zhu H, Peng W.
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source