Results 121 to 130 of about 1,270,105 (343)

Independent Orbiter Assessment (IOA): Analysis of the electrical power generation/fuel cell powerplant subsystem [PDF]

open access: yes
Results of the Independent Orbiter Assessment (IOA) of the Failure Modes and Effects Analysis (FMEA) and Critical Items List (CIL) are presented. The IOA approach features a top-down analysis of the hardware to determine failure modes, criticality, and ...
Bertsch, P. J., Brown, K. L.
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Evaluating the academic scientific laboratories' safety by applying failure mode and effect analysis (FMEA) at the public university in Lebanon. [PDF]

open access: yesHeliyon, 2023
Nasrallah I   +8 more
europepmc   +1 more source

Independent Orbiter Assessment (IOA): Analysis of the crew equipment subsystem [PDF]

open access: yes
The results of the Independent Orbiter Assessment (IOA) of the Failure Modes and Effects Analysis (FMEA) and Critical Items List (CIL) are presented. The IOA approach features a top-down analysis of the hardware to determine failure modes, criticality ...
Graham, L.   +3 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Independent Orbiter Assessment (IOA): Analysis of the DPS subsystem [PDF]

open access: yes
The results of the Independent Orbiter Assessment (IOA) of the Failure Modes and Effects Analysis/Critical Items List (FMEA/CIL) is presented. The IOA approach features a top-down analysis of the hardware to independently determine failure modes ...
Haufler, W. A.   +2 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Independent Orbiter Assessment (IOA): Analysis of the displays and controls subsystem [PDF]

open access: yes
The results of the Independent Orbiter Assessment (IOA) of the Failure Modes and Effects Analysis (FMEA) and Critical Items List (CIL) are presented. The IOA approach features a top-down analysis of the hardware to determine failure modes, criticality ...
Prust, E. E., Trahan, W. H.
core   +1 more source

Analisis Penyebab Cacat Produk Furniture Dengan Menggunakan Metode Failure Mode and Effect Analysis (Fmea) Dan Fault Tree Analysis (Fta) (Studi Kasus Pada PT. Ebako Nusantara) [PDF]

open access: yes, 2016
Analysis Cause Defect Products Furniture By Using The Method Failure Mode And Effect Analysis (FMEA) And Fault Tree Analysis (FTA) (Case Study In PT. Ebako Nusantara). PT. Ebako Nusantara is a company engaged in the field of furniture.
Arvianto, A. (Ary)   +2 more
core  

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