Results 51 to 60 of about 296,075 (303)
Failure Mode and Effect Analysis (FMEA) Application for Safety Risk Assessment Design of “X” Bakery
Companies in the food sector have 8 production process lines including: receiving raw materials, storing, making dough, baking, frying, cooling, packaging, and distributing.
Rizky Fajri Ramadhan +2 more
doaj +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Ship bunkering operations play a critical role in sustaining maritime transportation; however, they also entail significant risks to the environment, vessels, and crew.
B. Ceylan
semanticscholar +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FMEA (FAILURE MODE AND EFFECTS ANALYSIS) AND PROPOSAL OF RISK MINIMIZING IN STORAGE PROCESSES FOR AUTOMOTIVECLIENT [PDF]
There are several quality tools that support achievement of goals and ensure primary basis for promoting quality in enterprises. FMEA is a quantitative inductive method, which was created for the recognizing and evaluating of products ...
Kristína Ignáczová
doaj +1 more source
Security Application of Failure Mode and Effect Analysis (FMEA) [PDF]
Increasingly complex systems lead to an interweaving of security, safety, availability and reliability concerns. Most dependability analysis techniques do not include security aspects. In order to include security, a holistic risk model for systems is needed.
Christoph Schmittner +3 more
openaire +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source

