Results 51 to 60 of about 289,433 (344)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Discontinuous modelling of strain localisation and failure
, 2001 The computational simulation of failure in solids poses many challenges. A proper understanding of how structures respond under loading, both before and past the peak load, is important for safe and economical constructions.
Wells, G.N., Wells, G.N. (author)
core +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
INTECOMS: Journal of Information Technology and Computer Science, 2023 Pelabuhan merupakan suatu lokasi yang memiliki peran penting dan krusial dalam perkembangan industri dan perdagangan di suatu wilayah, serta merupakan salah satu kegiatan perdagangan yang berpotensi memberikan kontribusi bagi pertumbuhan dan perkembangan
Aqil Firdaus Aufa, S. S. Dahda
semanticscholar +1 more source
Integrating failure documentation with A3 template to improve product design quality [PDF]
, 2012 Design quality always has great impact on the competitive attribution of companies. Knowledge Management has become an important process which could help companies to accumulate the knowledge created in the past, and use it to solve the current problem ...
Zhu, Linjia
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Journal of Advanced Research in Applied Sciences and Engineering Technology, 2023 The article paper presents a strategic tool used in maintenance strategy deployment using failure mode and effect analysis method in oil and gas semi hermetic compressor perspective.
Ahmad Fuad Ab Ghani +5 more
semanticscholar +1 more source
Failure Mode and Effect Analysis (FMEA) Application for Safety Risk Assessment Design of “X” Bakery
Unnes Journal of Public Health, 2019 Companies in the food sector have 8 production process lines including: receiving raw materials, storing, making dough, baking, frying, cooling, packaging, and distributing.
Rizky Fajri Ramadhan +2 more
doaj +1 more source
Failure analysis of martensitic stainless steel bridge roller bearings
, 2017 The paper is aimed at finding the likely failure mechanism of a bridge roller bearing made of high strength martensitic stainless steel. Spectroscopy and finite element stress analysis of the roller indicated that an initial radial surface crack, found ...
Noury, Pourya, +3 more
core +1 more source