We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima +4 more
wiley +1 more source
Nonlinear temperature dependent failure analysis of finite width composite laminates [PDF]
A quasi-three dimensional, nonlinear elastic finite element stress analysis of finite width composite laminates including curing stresses is presented. Cross-ply, angle-ply, and two quasi-isotropic graphite/epoxy laminates are studied.
Herakovich, C. T., Nagarkar, A. P.
core +1 more source
ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori +8 more
wiley +1 more source
3PC-019 Risk management of cross-contamination of paediatric anti-cancer preparations using failure mode and effects criticality analysis [PDF]
M Alami Chentoufi +7 more
openalex +1 more source
Preliminary Reliability Analysis of Autonomous Underwater Vehicle in the Polar Environment based on Failure Mode and Effects Analysis and Fault Tree Analysis [PDF]
Hyonjeong Noh +2 more
openalex +1 more source
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
PRIORITIZATION OF IMPROVEMENT ACTIONS IN INDUSTRIAL PRODUCTION: APPLICATION OF THE FITRADEOFF METHOD TO ORDER IMPROVEMENT ACTIONS IDENTIFIED THROUGH THE FAILURES MODES AND EFFECTS ANALYSIS (FMEA) [PDF]
José Francisco Zanazzi +2 more
openalex +2 more sources
Using Failure Mode and Effects Analysis in Improving Nursing Blood Sampling at an International Specialized Cancer Center. [PDF]
Haroun A +6 more
europepmc +1 more source
Independent Orbiter Assessment (IOA): Assessment of the hydraulics/water spray boiler subsystem [PDF]
The results of the Independent Orbiter Assessment (IOA) of the Failure Modes and Effects Analysis (FMEA) and Critical Items List (CIL) are presented.
Bynum, M. C. +3 more
core +1 more source
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili +2 more
wiley +1 more source

