Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Failure Mode and Effects Analysis on the Air System of an Aero Turbofan Engine Using the Gaussian Model and Evidence Theory. [PDF]
Entropy (Basel), 2023 Tang Y, Zhou Y, Zhou Y, Huang Y, Zhou D.
europepmc +1 more source
Independent Orbiter Assessment (IOA): Assessment of instrumental subsystem FMEA/CIL [PDF]
The McDonnell Douglas Astronautics Company (MDAC) was selected in June 1986 to perform an Independent Orbiter Assessment (IOA) of the Failure Modes and Effects Analysis (FMEA) and Critical Items List (CIL).
Addis, A. W., Gardner, J. R.
core +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
FMEA and FTA Analyses of the Adhesive Joining Process using Electrically Conductive Adhesives [PDF]
, 2017 This paper introduces a formulation of appropriate risk estimation methods that can be used for improving of processes in the electronics area. Two risk assessment methods have been chosen with regard to the specifics of adhesive joining based on ...
Mach , P., Povolotskaya , E.
core
Failure Mode and Effect Analysis in Increasing the Revenue of Emergency Department
طب اورژانس ایران, 2015 Introduction: Successful performance of emergency department(ED) is one of the important indications of increasing the satisfaction among referees.
Farhad Rahmati +6 more
doaj
Application of failure mode and effects analysis to validate a novel hybrid Linac QC program that integrates automated and conventional QC testing. [PDF]
J Appl Clin Med Phys, 2022 Pearson M +6 more
europepmc +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
MethodsXThis study aimed to develop the Failure Mode and Effects Analysis (FMEA) and Decision Matrix Risk Assessment (DMRA) technique for the first time to assess risks associated with particulate matter (PM) and bioaerosol transmission in hospitals.
Mahbubeh Tangestani +3 more
doaj +1 more source