Results 31 to 40 of about 962,464 (311)

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee, Holly Evans, Claire E. Wakefield, Antoinette Anazodo, Richard J. Cohn, Brittany C. McGill, Elizabeth A. Lobb, Lori Wiener, Madeleine L. Juhrmann, Ursula M. Sansom‐Daly   +9 more
wiley   +1 more source

Failure Modes Analysis Related to User Experience in Interactive System Design Through a Fuzzy Failure Mode and Effect Analysis-Based Hybrid Approach

Applied Sciences
User experience (UX) is crucial for interactive system design. To improve UX, one method is to identify failure modes related to UX and then take action on the high-priority failure modes to decrease their negative impacts.
Yongfeng Li, Liping Zhu
doaj   +1 more source

Interaction of crippling and torsional-flexural instabilities for centrally loaded columns [PDF]

, 1970
Empirical technique predicts failure loads for centrally loaded columns with thin-walled, open cross sections.
Walls, J. C.
core   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

System dynamic reliability evaluation of multiple failure modes of earth dams subjected to strong earthquake excitation

Soils and Foundations, 2023
An earth dam in service is a complex system that has different dynamic failure modes under different ground motion excitations with a certain correlation between the different failure modes.
Min Xiong, Wenwen Wang, Yu Huang
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Research on Failure Characteristics of Concrete Three-Point Bending Beams with Preexisting Cracks in Different Positions Based on Numerical Simulation

Geofluids, 2021
Concrete three-point bending beams with preexisting cracks are widely used to study the growth process of I-II mixed mode cracks. Studying the failure characteristics of preexisting cracks at different locations on concrete three-point bending beams not ...
Liuqun Zhao, Li Zheng, Hui Qin, Tiesuo Geng, Yonggang Tan, Zhe Zhang   +5 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Identifying risk characteristics using failure mode and effect analysis for risk management in online magnetic resonance-guided adaptive radiation therapy

Physics and Imaging in Radiation Oncology, 2022
Background and purpose: Online magnetic resonance-guided adaptive radiotherapy (MRgART) is a new technology of radiotherapy and requires a new quality control program in many aspects.
Shie Nishioka, Hiroyuki Okamoto, Takahito Chiba, Tatsuya Sakasai, Kae Okuma, Junichi Kuwahara, Daisuke Fujiyama, Satoshi Nakamura, Kotaro Iijima, Hiroki Nakayama, Mihiro Takemori, Yuuki Tsunoda, Keita Kaga, Hiroshi Igaki   +13 more
doaj   +1 more source