Results 61 to 70 of about 954,912 (290)

Automated Mixed Traffic Vehicle (AMTV) technology and safety study [PDF]

open access: yes
Technology and safety related to the implementation of an Automated Mixed Traffic Vehicle (AMTV) system are discussed. System concepts and technology status were reviewed and areas where further development is needed are identified.
Johnston, A. R.   +3 more
core   +1 more source

Development of a robust structural health monitoring system for wind turbine foundations [PDF]

open access: yes, 2012
The construction of onshore wind turbines has rapidly been increasing as the UK attempts to meet its renewable energy targets. As the UK’s future energy depends more on wind farms, safety and security are critical to the success of this renewable energy ...
Currie, Magnus   +2 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Estimating the Theoretical and Empirical Probability Coefficients of Oil Pipeline Transport Infrastructure Failure Modes in Nigeria’s Coastal Ecosystem: Panacea for Non Optimal Deployment of Pipeline Safety and Security Management Systems

open access: yesLogi, 2018
Failure of oil pipeline transport infrastructure in Nigeria’s coastal ecosystem has continued to pose serious environmental problems with consequent economic effects.
Nwokedi Theophilus Chinonyerem   +1 more
doaj   +1 more source

Compression failure of angle-ply laminates [PDF]

open access: yes
The present work deals with modes and mechanisms of failure in compression of angle-ply laminates. Experimental results were obtained from 42 angle-ply IM7/8551-7a specimens with a lay-up of ((plus or minus theta)/(plus or minus theta)) sub 6s where ...
Hyer, Michael W.   +2 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Numerical Investigation of Bedding Rock Slope Potential Failure Modes and Triggering Factors: A Case Study of a Bridge Anchorage Excavated Foundation Pit Slope

open access: yesApplied Sciences
The analysis of slope failure modes is essential for understanding slope stability. This study investigated the failure modes and triggering factors of a rock slope using the limit equilibrium method, finite differences method, and exploratory factor ...
Songling Han, Changming Wang
doaj   +1 more source

Independent Orbiter Assessment (IOA): Assessment of the life support and airlock support systems, volume 1 [PDF]

open access: yes
The results of the Independent Orbiter Assessment (IOA) of the Failure Modes and Effects Analysis (FMEA) and Critical Items List (CIL) are presented. The IOA effort first completed an analysis of the Life Support and Airlock Support Systems (LSS and ALSS)
Arbet, J. D.   +3 more
core   +1 more source

An aging evaluation of the bearing performances of glass fiber composite laminate in salt spray fog environment [PDF]

open access: yes, 2019
The aim of the present paper is to assess the bearing performance evolution of pinned, glass-composite laminates due to environmental aging in salt-spray fog tests.
Bruzzaniti P. G.   +4 more
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

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