Results 91 to 100 of about 2,648,329 (307)

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

An efficient method to compute the failure probability

, 2015
This paper presents an efficient method to compute the failure probability of a geotechnical system, which is based upon numerical integration of the cumulative distribution function (CDF) of the performance function.
Juang, C. Hsein, Martin, James R., Zhang, Jie, Gong, Wenping   +3 more
core   +1 more source

Reliability Analysis of Three-Dimensional Slopes Considering the Soil Spatial Variability Based on Particle Swarm Optimization Algorithm

Applied Sciences
This paper presents a new algorithm for assessing the reliability of three-dimensional (3D) slope stability considering the spatial variability of soil based on the Particle Swarm Optimization (PSO) algorithm.
Xin Chen, Jiale Xu, Yukuai Wan, Rong Yang, Jiewen Sun, Di Wu   +5 more
doaj   +1 more source

Probability of default models of Russian banks [PDF]

This paper presents results from an econometric analysis of Russian bank defaults during the period 1997–2003, focusing on the extent to which publicly available information from quarterly bank balance sheets is useful in predicting future defaults ...
Peresetsky, Anatoly A., Golovan, Sergei V., Karminsky, Alexandr A.   +2 more
core  

A More Powerful Step-up Procedure for Controlling the False Discovery Rate under Independence

, 2002
10.1016/S0167-7152(01)00196-1Statistics and Probability Letters562217 ...
KWONG, Koon Shing, Kwong, K.-S., Wong, E.-H., Koon-Shing Kwong, Wong, Ee Hwee, Ee-Hwee Wong   +5 more
core   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Structural reliability analysis based on a limited directional important sampling simulation

Nihon Kikai Gakkai ronbunshu, 2015
This study describes an efficient estimation method of the structural failure probability based on a limited directional importance sampling simulation.
Shoya OKUDA, Masaaki YONEZAWA
doaj   +1 more source

Computing Synchronizer Failure Probabilities [PDF]

2007 Design, Automation & Test in Europe Conference & Exhibition, 2007
Suwen Yang, Mark R. Greenstreet
openaire   +2 more sources

Coordinated failure? a cross-country bank failure prediction model [PDF]

This paper empirically investigates the causes of bank failures in Japan and Indonesia. Using logistic regression analysis of financial ratios, we explore the usefulness of domestic bank failure prediction models with a cross-country model that allows ...
Besar, Dwityapoetra, Montgomery, Heather, Santoso, Wimboh, Hanh, Tran   +3 more
core  

IV Thrombolysis Facilitates Interventional Reperfusion in Non‐Cardioembolic but Not Cardioembolic Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi, Daniel P. O. Kaiser, Martin Arndt, Norma J. Diel, Erik Simon, Witold H. Polanski, Volker Puetz, Hagen B. Huttner, Timo Siepmann   +8 more
wiley   +1 more source