Results 71 to 80 of about 442,844 (266)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Failure Probability Prediction of Thermally Stable Diamond Composite Tipped Picks in the Cutting Cycle of Underground Roadway Development

open access: yesApplied Sciences, 2019
The Thermally Stable Diamond Composite (TSDC) tipped pick has been developed to replace Tungsten Carbide (WC) tipped picks for hard rock cutting. Due to the material properties of TSDC, a major failure mode of TSDC tipped picks during rock cutting is ...
Yong Sun, Xingsheng Li, Hua Guo
doaj   +1 more source

Does Information Transparency Decrease Coordination Failure? [PDF]

open access: yes
This study experimentally tests the effect of information transparency on the probability of coordination failure in global games with finite signals.
Regina M. Anctil   +3 more
core  

On Buffered Failure Probability in Design and Optimization of Structures [PDF]

open access: yes, 2009
Reliability Engineering & System SafetyIn reliability engineering focused on the design and optimization of structures, the typical measure of reliability is the probability of failure of the structure or its individual components relative to specific ...
Royset, J.O.   +3 more
core   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji   +13 more
wiley   +1 more source

On mixture failure rate ordering [PDF]

open access: yes
Mixtures of increasing failure rate distributions (IFR) can decrease at least in some intervals of time. Usually this property can be observed asymptotically as time tends to infinity.
Maxim S. Finkelstein, Veronica Esaulova
core  

Failure Probability Under Parameter Uncertainty

open access: yes, 2010
In many problems of risk analysis, failure is equivalent to the event of a random risk factor exceeding a given threshold. Failure probabilities can be controlled if a decisionmaker is able to set the threshold at an appropriate level.
Gerrard, R. J. G.   +3 more
core   +1 more source

Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang   +22 more
wiley   +1 more source

Asymptotic behavior of mixture failure rates [PDF]

open access: yes
Mixtures of increasing failure rate distributions (IFR) can decrease at least in some intervals of time. Usually this property is observed asymptotically as time tends to infinity , which is due to the fact that a mixture failure rate is ‘bent down’, as ...
Maxim S. Finkelstein, Veronica Esaulova
core  

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina   +11 more
wiley   +1 more source

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