Flexural fatigue strength and failure probability of concrete beam containing nano-silica and steel fibers [PDF]
Roller-compacted concrete (RCC) shares components with conventional concrete but differs in aggregate size, workability, mix design, and construction methods.
Yaghoub Mohammadi, Hassan Rezaei Dolagh
doaj +1 more source
Study of Reliability for Main Components and Devices of Die-Cutting Presses for Packaging
A large variety of machine operating conditions leads to a difference in the wear rate even for their units being of the same type. Operational time terms of single-type units and machines are not the same, and therefore, numerical expressions of ...
N. S. Kohnenko +2 more
doaj +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Heterotropic regulation and negative homotropic cooperativity
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Analysis method of brittle failure probability of steel members
In recent years, researchers have been proposed various analytical methods to calculate the structural reliability. However, a series of low stress brittle fracture accidents occurred in steel structure, the brittle failure of steel members cannot be ...
Cheng Yang +5 more
core +1 more source
Sequential design of computer experiments for the estimation of a probability of failure [PDF]
International audienceThis paper deals with the problem of estimating the volume of the excursion set of a function $f:\mathbb{R}^d \to \mathbb{R}$ above a given threshold, under a probability measure on $\RR^d$ that is assumed to be known.
Vazquez, E. +14 more
core +2 more sources
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
The Market's View on the Probability of Banking Sector Failure: Cross-Country Comparisons [PDF]
Considering the increasingly international banks of today, the health of a country's banking sector is crucial not only to the country's growth and prosperity but also to the rest of the international financial community.
Hans Byström
core
Ethical Foreground and Background in Adult Educator Work
ABSTRACT Adult educators work in a complex ethical environment. The very act of contributing to the learning of another is fraught with moral overtones. In this paper we consider the ethical dimensions of adult educator practice by distinguishing the ethical features of the context or ‘background’ of practice from the ethical capabilities and decision ...
Steven Hodge, Sonal Nakar
wiley +1 more source
Does Information Transparency Decrease Coordination Failure? [PDF]
This study experimentally tests the effect of information transparency on the probability of coordination failure in global games with finite signals.
Regina M. Anctil +3 more
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