Results 51 to 60 of about 442,844 (266)
Treatment failure probability.
, 2018 Treatment failure probability.
Laura Galli (3623459) +11 more
core +1 more source
Sequential design of computer experiments for the estimation of a probability of failure [PDF]
, 2011 International audienceThis paper deals with the problem of estimating the volume of the excursion set of a function $f:\mathbb{R}^d \to \mathbb{R}$ above a given threshold, under a probability measure on $\RR^d$ that is assumed to be known.
Vazquez, E. +14 more
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Predicting the Probability of Failure of Cementitious Sewer Pipes Using Stochastic Finite Element Method [PDF]
, 2015 In this paper, a stochastic finite element method (SFEM) is employed to investigate the probability of failure of cementitious buried sewer pipes subjected to combined effect of corrosion and stresses.
Alani, Amir M. +5 more
core +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Cumulative Failure Probability of Deteriorating Structures: Can It Drop?
, 2021 The reliability of deteriorating structures at time t is quantified by the probability that failure occurs within the period leading up to time t. This probability is often referred to as cumulative failure probability and is equal to the cumulative ...
Schneider, Ronald +3 more
core +2 more sources
Applied SciencesA reliability analysis can become intricate when addressing issues related to nonlinear implicit models of complex structures. To improve the accuracy and efficiency of such reliability analyses, this paper presents a surrogate model based on an adaptive
Feng Zhang +4 more
doaj +1 more source
Reliability analysis of two-unit cold standby repairable systems under Poisson shock. [PDF]
, 2011 This paper analyses the reliability of a cold standby system consisting of two re- pairable units, a switch and a repairman. At any time, one of the two units is operating while the other is on cold standby.
Shaomin Wu +3 more
core +1 more source