Results 61 to 70 of about 2,648,329 (307)
Regional sensitivity on failure probability (RS-FP) can quantify the effect of the input region of interest (IRoI) on the failure probability and provide useful information for reliability based design optimization.
Jingyu Lei +3 more
doaj +1 more source
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
An Innovative Linear Wireless Sensor Network Reliability Evaluation Algorithm
In recent years, wireless sensor networks (WSNs) have become a crucial technology for infrastructure monitoring. To ensure the reliability of monitoring services, evaluating the network’s reliability is particularly important.
Tao Ma, Huidong Guo, Xin Li
doaj +1 more source
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Weibull Failure Probability Estimation Based on Zero-Failure Data [PDF]
Reliability testing is often carried out with small sample sizes and short duration because of increasing costs and the restriction of development time. Therefore, for highly reliable products, zero-failure data are often collected in such tests, which could not be used to evaluate reliability by traditional methods.
Jiang, Ping +3 more
openaire +1 more source
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Multiple Factors Coupling Probability Calculation Model of Transmission Line Ice-Shedding
After a transmission line is covered by ice in winter, ice-shedding and vibration occurs under special meteorological and external dynamic conditions, which leads to intense transmission line shaking.
Hao Pan +5 more
doaj +1 more source
Reliability analysis of pipeline in fault area based on BP-MC method
Strike-slip fault is a common geologic hazard for buried pipelines. The fault-induced ground displacement often leads to excessive deformation and failure of pipelines, so it is of great significance to carry out reliability analysis of pipelines in ...
Qian ZHENG, Hong ZHANG, Xiaoben LIU
doaj +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Reliability Assessment of Tapered Stress Joint under Inclined Wellhead of TLP
To study the influence of random variables on the reliability of tapered stress joint strength, a reliability calculation method based on Kriging model is proposed.
Wang Kang +5 more
doaj

