Results 71 to 80 of about 45,359 (268)
Molecular Oncology, EarlyView.Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
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Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
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Molecular Oncology, EarlyView.Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla +5 more
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Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
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Note on the failure rate characterizations
Bulletin of the Faculty of Science, Ibaraki University. Series A, Mathematics, 1988 Recently, many authors discussed on the failure rate of a probability density function. The hazard function, or the failure rate is defined as \[ h(t)=f(t)/(1-F(t)),\quad 0\leq F(t)
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Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
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CLINICAL STUDIES OF THE BLOOD VOLUME. III. CHANGES IN BLOOD VOLUME, VENOUS PRESSURE AND BLOOD VELOCITY RATE IN CHRONIC CONGESTIVE HEART FAILURE [PDF]
, 1937 John G. Gibson, William A. Evans
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Remarks on the Failure Rate Characterizations
Bulletin of the Faculty of Science, Ibaraki University. Series A, Mathematics, 1986 The failure rate, or the hazard function is defined as \(r(t)=f(t)/(1- F(t))\), \(0\leq F(t)0\) for all \(t>0\), and \(\int^{\infty}_{0}f(t)dt=1\). We also assume that f(t) is continuous and twice differentiable on (0,\(\infty)\).
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Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
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TecnoLógicas, 2019 Network operators work constantly to maintain an appropriate level of reliability in their power supply and to preserve the integrity of the vegetation growing underneath overhead power distribution systems.
Johan S. Correa-Tamayo +2 more
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