Results 71 to 80 of about 2,827,460 (258)
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Aggregate economy risk and company failure: An examination of UK quoted firms in the early 1990s [PDF]
, 2003 Considerable attention has been directed in the recent finance and economics literature to issues concerning the effects on company failure risk of changes in the macroeconomic environment.
Hunter, J, Isachenkova, N
core
Frontiers in MedicineBackgroundThe conventional midline approach for lumbar puncture (MAT-LP) has a relatively low success rate of 70%. The paramedian approach can increase the effective puncture area and success rate but lacks standardized guidelines. This study evaluated a
Yuan-Dong Zhuang +7 more
doaj +1 more source
The power law character of off-site power failures [PDF]
arXiv, 2003 A study on the behavior of off-site AC power failure recovery times at three nuclear plant sites is presented. It is shown, that power law is appropriate for the representation of failure frequency-duration correlation function of off-site power failure events, based on simple assumptions about component failure and repair rates.
arxiv
FEBS Letters, EarlyView.UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg +2 more
wiley +1 more source
Creep rupture of materials: insights from a fiber bundle model with relaxation
, 2010 I adapted a model recently introduced in the context of seismic phenomena, to study creep rupture of materials. It consists of linear elastic fibers that interact in an equal load sharing scheme, complemented with a local viscoelastic relaxation ...
E. A. Jagla, H. Kawamura, K. Yamaguchi
core +1 more source
Failure Analysis and Quantification for Contemporary and Future Supercomputers [PDF]
arXiv, 2019 Large-scale computing systems today are assembled by numerous computing units for massive computational capability needed to solve problems at scale, which enables failures common events in supercomputing scenarios. Considering the demanding resilience requirements of supercomputers today, we present a quantitative study on fine-grained failure ...
arxiv
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Fire Risk in MTBF Evaluation for UPS System
Advances in Electrical and Electronic Engineering, 2016 The reliability improvement of no-break redundant electrical systems is the first aim of the proposed strategy. The failure of some UPS (Uninterruptible Power Supply) system may lead to the fire occurrence.
Stefano Elia, Alessio Santantonio
doaj +1 more source
Molecular Oncology, EarlyView.Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker +14 more
wiley +1 more source