Results 71 to 80 of about 547,453 (314)
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
A Design of Workflow-Based Automated Failure Recovery Framework in IoT Edge Environment
IEEE AccessIn IoT Edge environments, microservice-based architectures decompose workloads into functional units for efficient deployment and scaling across edge nodes.
Phuong Bac Ta +2 more
doaj +1 more source
Techniques for Failure Recovery in a Software-Defined Network
, 2014 As our lives become ever more dependent on network connectivity, it becomes increasingly more important for networks to be able to overcome the failure of individual components and continue to function.
Lorier, Christopher Martin +1 more
core
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Perceived justice in email service recovery
, 2007 This study adds to the limited research of service recovery in an online environment, drawing on data from Australia. It is perhaps the first non-US study of email service recovery as well as the first to apply a theoretical perspective - perceived ...
Neale, L.G., Murphy, J.
core
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
vFFR: A Very Fast Failure Recovery Strategy Implemented in Devices With Programmable Data Plane
IEEE Open Journal of the Communications SocietyThe rapid emergence of new applications and services, and their increased demand for Quality of Service (QoS), have a significant impact on the development of today’s communication networks.
David Franco +4 more
doaj +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source