Results 71 to 80 of about 1,548,929 (297)

DeepPR: Progressive Recovery for Interdependent VNFs with Deep Reinforcement Learning [PDF]

, 2016
The increasing reliance upon cloud services entails more flexible networks that are realized by virtualized network equipment and functions. When such advanced network systems face a massive failure by natural disasters or attacks, the recovery of the ...
Devic, Siddartha, Gour, Riti, Ishigaki, Genya, Jue, Jason P.   +3 more
core   +3 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Speedy Routing Recovery Protocol for Large Failure Tolerance in Wireless Sensor Networks

Sensors, 2010
Wireless sensor networks are expected to play an increasingly important role in data collection in hazardous areas. However, the physical fragility of a sensor node makes reliable routing in hazardous areas a challenging problem.
Joa-Hyoung Lee, In-Bum Jung
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

DetNet service share protection scheme based on SRv6

Tongxin xuebao, 2021
To solve the problem that existing methods are difficult to achieve efficient deployment and service protection in deterministic network (DetNet), a DetNet service protection architecture based on SRv6 was proposed.By leveraging this architecture, a ...
Shuopeng LI, Juan FANG, Ken CHEN
doaj  

Software control for large scale on-board checkout: A concept [PDF]

, 1972
Two level system checkout in which first level satisfies continuous monitoring requirements and second level provides fault isolation to satisfy maintenance requirements, provides self-checking capability for monitoring system and enables recovery from ...
Grounds, H. K., Norton, D. H., Jr.
core   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Heart Failure Risk in Patients With Systemic Autoimmune Inflammatory Diseases

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Cardiac disease, including heart failure (HF), is a significant cause of morbidity and mortality for patients with systemic autoimmune inflammatory diseases (SAIDs).
Alexia A. Zagouras, Pieter Martens, W. H. Wilson Tang   +2 more
doaj   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Full nitrogen recovery and potable water production from human urine by membrane distillation [PDF]

, 2016
Human urine offers some interesting possibilities for ammonia and potable water recovery. Membrane distillation holds possible advantages over existing urine treatment technologies, specifically regarding ammonia recovery.
Derese, Sebastiaan, Verliefde, Arne
core