Results 81 to 90 of about 1,548,929 (297)
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
A Design of Workflow-Based Automated Failure Recovery Framework in IoT Edge Environment
In IoT Edge environments, microservice-based architectures decompose workloads into functional units for efficient deployment and scaling across edge nodes.
Phuong Bac Ta +2 more
doaj +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata +13 more
wiley +1 more source
vFFR: A Very Fast Failure Recovery Strategy Implemented in Devices With Programmable Data Plane
The rapid emergence of new applications and services, and their increased demand for Quality of Service (QoS), have a significant impact on the development of today’s communication networks.
David Franco +4 more
doaj +1 more source
COMPREHENSIVE DISASTER MANAGEMENT AND DEVELOPMENT: THE ROLE OF GEOINFORMATICS AND GEO-COLLABORATION IN LINKING MITIGATION AND DISASTER RECOVERY IN THE EASTERN CARIBBEAN [PDF]
The recurring failure of communities at risk to build mitigation into disaster recovery activities to reduce risks against future disaster events remains unresolved.
Huggins, Leonard James
core
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
Real‐time text tracking in natural scenes
The authors present a system that automatically detects, recognises and tracks text in natural scenes in real‐time. The focus of the author's method is on large text found in outdoor environments, such as shop signs, street names, billboards and so on ...
Carlos Merino‐Gracia, Majid Mirmehdi
doaj +1 more source

