Results 61 to 70 of about 190,306 (282)

Fair Play: Origin and meanings in sport and society [PDF]

open access: yes, 2019
Una versión de este artículo en inglés se publicó en el año 2009 en la revista Kinesiology de la Universidad de Zagreb, en su número 41 (2), pp. 5-18, bajo la autoría de Roland Renson.
Renson, Roland
core   +2 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Sport against the threats of the modern world

open access: yesJournal of Education, Health and Sport, 2018
The study points out the problem of sports threats in the face of threats in the modern world, ie commercialization, dehumanization, doping, aggression of the sports audience, and what is connected with this attempt to win by athletes at all costs.
Jolanta Elżbieta Kowalska
doaj   +3 more sources

Lex sportiva and fair-play

open access: yesZbornik Radova Pravnog Fakulteta u Splitu, 2011
Basically the work consists of the denial of a claim, which is largely entrenched in doctrine, according to which lex sportiva represents a transnational or non-national legal system, on the one hand, and affirmation of fair-play, as the principle that ...
Miodrag Mićović
doaj  

UEFA Financial Fair Play –Förändring inom regelverket [PDF]

open access: yes, 2016
Bakgrund och problemdiskussion Fotboll är världens största sport och fotbollsklubbar fyller viktiga funktioner i samhället. En ekonomiskt ohållbar situation uppstod bland europeiska fotbollsklubbar som UEFA angrep med införandet av FFP-regelverket ...
Mirza, Enlil, Todorovic, Nebojsa
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

The principle of fair play in the aspect of responsibility in the opinion of junior high schools students-supporting sport clubs in Lodz

open access: yesJournal of Education, Health and Sport, 2018
The idea of fair play can play an important role in the education process, especially among students of adolescence (middle school age). In Lodz, this is particularly important because there is a problem of stadium hooliganism, which is particularly ...
Jolanta Elżbieta Kowalska
doaj   +3 more sources

Sport, olimpizm i zasada „fair play” jako wartości w życiu osób niepełnosprawnych [PDF]

open access: yes, 2013
Uniwersalny charakter sportu, jego korzyści dla rozwoju fizycznego, emocjonalnego i społecznego wraz z wychowawczymi walorami uczestnictwa w określonych formach aktywności fizycznej są skutecznym środkiem do eliminacji stygmatu związanego z ...
Kaźmierczak, Arkadiusz
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

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