Results 91 to 100 of about 5,339,965 (304)

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

[Second] annual fair of the Ellis County Fair Association ...

open access: yes, 1888
Publication describing the Annual fair of Ellis County ...
Ellis County Fair Association (Tex.). Annual Fair.
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Comal County ... annual fair, Comal Fair Association.

open access: yes, 1901
A catalog for the Comal County fair, primarily containing advertisements.Page numeration not in correct order. Description based on: 7th (1901); title from cover.
Comal Fair Association
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Implementing fair lending practices: Advanced data analytics approaches and regulatory compliance

open access: yes
Implementing fair lending practices is crucial for financial institutions to ensure equal access to credit and comply with regulatory requirements. Advanced data analytics approaches offer powerful tools for detecting and mitigating potential biases in ...
Oluwaseun Adeola Bakare   +2 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Cultural and Linguistic Fairness in the Assessment of Semantics [PDF]

open access: yesSeminars in Speech and Language, 2004
In creating a semantic assessment that will be linguistically and culturally fair, it is important to avoid the bias of acquired vocabulary tests. This article describes techniques to assess children's processing of new words, their lexical organization and retrieval, which may be more significant than the number of words known.
openaire   +2 more sources

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Nolan County Fair

open access: yes, 1924
A pamphlet with advertisements, a list of staff and prizes for the Nolan County ...
Nolan County Fair
core  

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