Results 101 to 110 of about 5,339,965 (304)
Journal of Human ServicesChild Protective Services is responsible for keeping children and families safe by making determinations about whether allegations of abuse and neglect should be substantiated, yet the decision-making systems that guide their actions are prone to ...
Danielle Mitnick +4 more
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Catalogue ... annual Burnet County Fair
, 1934 A catalog for the Burnett County fair, primarily containing ...
Burnet County Fair (Bertram, Tex.)
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Fairness Measures for Biometric Quality Assessment
Abstract Quality assessment algorithms measure the quality of a captured biometric sample. Since the sample quality strongly affects the recognition performance of a biometric system, it is essential to only process samples of sufficient quality and discard samples of low-quality.
André Dörsch +4 more
openaire +3 more sources
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
A Fair Assessment of Evaluation Tools for the Murine Microbead Occlusion Model of Glaucoma. [PDF]
Int J Mol Sci, 2021 Claes M +8 more
europepmc +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Measuring FAIR Principles to Inform Fitness for Use
International Journal of Digital Curation, 2018 For open science to flourish, data and any related digital outputs should be discoverable and re-usable by a variety of potential consumers. The recent FAIR Data Principles produced by the Future of Research Communication and e-Scholarship (FORCE11 ...
Bradley Wade Bishop, Carolyn Hank
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
, 1962 These biennial reports are summaries of the activities of this agency. They were extracted from a series of Kansas agency reports covering over 100 state agencies and institutions bound together for each biennium., 1959/1960 - 1979/1980.
Kansas. Board of State Fair Managers.
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