Results 191 to 200 of about 24,500,580 (267)

Advances, challenges, and future directions in trauma-related Findable, Accessible, Interoperable, Reusable (FAIR) data efforts. [PDF]

J Trauma Stress
O'Neil M, de Haan A, Sadeh Y, Marsac ML, Kassam-Adams N, Morgan-Lopez A, Hamblen J, Clauss K, Hien D.   +8 more
europepmc   +1 more source

Developing a framework for open and FAIR data management practices for next generation risk- and benefit assessment of fish and seafood. [PDF]

EFSA J, 2022
Pineda-Pampliega J, Bernhard A, Hannisdal R, Ørnsrud R, Mathisen GH, Solstad G, Rasinger JD.   +6 more
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Comparative Effectiveness of DHIS2 and FAIR Data Approaches for Privacy-Preserving Health Data Analytics in Uganda: A Systematic Review. [PDF]

Clinicoecon Outcomes Res
Basajja M, Paul-Chima UO.
europepmc   +1 more source

From biomedical cloud platforms to microservices: next steps in FAIR data and analysis. [PDF]

Sci Data, 2022
Sheffield NC, Bonazzi VR, Bourne PE, Burdett T, Clark T, Grossman RL, Spjuth O, Yates AD.   +7 more
europepmc   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Order from entropy: big data from FAIR data cohorts in the digital age of plant breeding. [PDF]

Theor Appl Genet
Gogna A, Arend D, Beier S, Rezaei EE, Würschum T, Zhao Y, Chu J, Reif JC.   +7 more
europepmc   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

FAIR data - the photon and neutron communities move together towards open science. [PDF]

IUCrJ
Murphy BM, Götz A, Gutt C, McGuinness C, Rønnow HM, Schneidewind A, Deledda S, Pietsch U.   +7 more
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source