Results 251 to 260 of about 2,294,345 (331)

Don't Just Be FAIR—Be Found! Best practices to increase the impact of your research data

Valentina Caracuta
openalex   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Erratum: Recommendations for Services in a FAIR Data Ecosystem. [PDF]

Patterns (N Y), 2020
Koers H, Bangert D, Hermans E, van Horik R, de Jong M, Mokrane M.   +5 more
europepmc   +1 more source

From Data to Equity: Predicting and Auditing Fairness in Indian Bail Decisions

Sneha Deshmukh, Prathmesh Kamble
openalex   +1 more source

First, Open Access, then Open (and FAIR) Data, now Open Citations.

, 2018
Henry S. Rzepa
openalex   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Enabling FAIR data stewardship in complex international multi-site studies: Data Operations for the Accelerating Medicines Partnership® Schizophrenia Program. [PDF]

Schizophrenia (Heidelb)
Billah T, Cho KIK, Borders O, Chung Y, Ennis M, Jacobs GR, Liebenthal E, Mathalon DH, Mohandass D, Nicholas SC, Pasternak O, Penzel N, Eichi HR, Wolff P, Anticevic A, Laulette K, Nunez AR, Tamayo Z, Buccilli K, Colton BL, Dwyer DB, Hendricks L, Yuen HP, Spark J, Tod S, Carrington H, Chen JT, Coleman MJ, Corcoran CM, Haidar A, John O, Kelly S, Marcy PJ, Matneja P, McGowan A, Ray SE, Veale S, Winter-Van Rossum I, Addington J, Allott KA, Calkins ME, Clark SR, Gur RC, Harms MP, Perkins DO, Ruparel K, Stone WS, Torous J, Yung AR, Zoupou E, Fusar-Poli P, Mittal VA, Shah JL, Wolf DH, Cecchi G, Kapur T, Kubicki M, Lewandowski KE, Bearden CE, McGorry PD, Kahn RS, Kane JM, Nelson B, Woods SW, Shenton ME, Accelerating Medicines Partnership® Schizophrenia (AMP® SCZ), Baker JT, Bouix S.   +67 more
europepmc   +1 more source

How FAIR are the data associated with the 2017 Molecules-of-the-Year?

, 2018
Henry S. Rzepa
openalex   +1 more source

Data models to GO-FAIR [PDF]

Nature Genetics, 2017
openaire   +2 more sources