Results 231 to 240 of about 444,200 (304)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Fair Data, Bayesian Statistics and Human Cohort Studies: Current Trends in Metabolomic Research. [PDF]

Metabolites
Fiehn O.
europepmc   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Building a FAIR data ecosystem for incorporating single-cell transcriptomics data into agricultural genome to phenome research. [PDF]

Front Genet
Kapoor M, Ventura ES, Walsh A, Sokolov A, George N, Kumari S, Provart NJ, Cole B, Libault M, Tickle T, Warren WC, Koltes JE, Papatheodorou I, Ware D, Harrison PW, Elsik C, Yordanova G, Burdett T, Tuggle CK.   +18 more
europepmc   +1 more source

FAIRness in Biomedical Data Discovery

Proceedings of the 12th International Joint Conference on Biomedical Engineering Systems and Technologies, 2019
Alina Trifan, José Luís Oliveira
openaire   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Understanding the provenance and quality of methods is essential for responsible reuse of FAIR data. [PDF]

Nat Med
Weissgerber TL, Gazda MA, Nilsonne G, Ter Riet G, Cobey KD, Prieß-Buchheit J, Noro J, Schulz R, Tijdink JK, Bobrov E, Bannach-Brown A, Franzen DL, Moschini U, Naudet F, Mansmann U, Salholz-Hillel M, Bandrowski A, Macleod MR.   +17 more
europepmc   +1 more source

Erratum: Recommendations for Services in a FAIR Data Ecosystem. [PDF]

Patterns (N Y), 2020
Koers H, Bangert D, Hermans E, van Horik R, de Jong M, Mokrane M.   +5 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

FAIR principles for data stewardship [PDF]

Nature Genetics, 2016
openaire   +2 more sources