Results 221 to 230 of about 24,500,580 (267)

Enabling FAIR data stewardship in complex international multi-site studies: Data Operations for the Accelerating Medicines Partnership® Schizophrenia Program. [PDF]

Schizophrenia (Heidelb)
Billah T, Cho KIK, Borders O, Chung Y, Ennis M, Jacobs GR, Liebenthal E, Mathalon DH, Mohandass D, Nicholas SC, Pasternak O, Penzel N, Eichi HR, Wolff P, Anticevic A, Laulette K, Nunez AR, Tamayo Z, Buccilli K, Colton BL, Dwyer DB, Hendricks L, Yuen HP, Spark J, Tod S, Carrington H, Chen JT, Coleman MJ, Corcoran CM, Haidar A, John O, Kelly S, Marcy PJ, Matneja P, McGowan A, Ray SE, Veale S, Winter-Van Rossum I, Addington J, Allott KA, Calkins ME, Clark SR, Gur RC, Harms MP, Perkins DO, Ruparel K, Stone WS, Torous J, Yung AR, Zoupou E, Fusar-Poli P, Mittal VA, Shah JL, Wolf DH, Cecchi G, Kapur T, Kubicki M, Lewandowski KE, Bearden CE, McGorry PD, Kahn RS, Kane JM, Nelson B, Woods SW, Shenton ME, Accelerating Medicines Partnership® Schizophrenia (AMP® SCZ), Baker JT, Bouix S.   +67 more
europepmc   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

FAIR data retrieval for sensitive clinical research data in Galaxy. [PDF]

Gigascience
Ouwerkerk J, Rasche H, Spalding JD, Hiltemann S, Stubbs AP.   +4 more
europepmc   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

A Framework for the Interoperability of Cloud Platforms: Towards FAIR Data in SAFE Environments. [PDF]

Sci Data
Grossman RL, Boyles RR, Davis-Dusenbery BN, Haddock A, Heath AP, O'Connor BD, Resnick AC, Taylor DM, Ahalt S.   +8 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

From Planning Stage Towards FAIR Data: A Practical Metadatasheet For Biomedical Scientists. [PDF]

Sci Data
Seep L, Grein S, Splichalova I, Ran D, Mikhael M, Hildebrand S, Lauterbach M, Hiller K, Ribeiro DJS, Sieckmann K, Kardinal R, Huang H, Yu J, Kallabis S, Behrens J, Till A, Peeva V, Strohmeyer A, Bruder J, Blum T, Soriano-Arroquia A, Tischer D, Kuellmer K, Li Y, Beyer M, Gellner AK, Fromme T, Wackerhage H, Klingenspor M, Fenske WK, Scheja L, Meissner F, Schlitzer A, Mass E, Wachten D, Latz E, Pfeifer A, Hasenauer J.   +37 more
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

MetaXtract: Extracting Metadata from Raw Files for FAIR Data Practices and Workflow Optimisation

Lutfi A, Chen ZA, Fischer L, Rappsilber J.   +3 more
europepmc   +1 more source

Editorial: Navigating the landscape of FAIR data sharing and reuse: repositories, standards, and resources. [PDF]

Front Neuroinform
van Swieten MMH, Haselgrove C.
europepmc   +1 more source