Results 221 to 230 of about 444,200 (304)

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

The state of food composition databases: data attributes and FAIR data harmonization in the era of digital innovation. [PDF]

Front Nutr
Brinkley S, Gallo-Franco JJ, Vázquez-Manjarrez N, Chaura J, Quartey NKA, Toulabi SB, Odenkirk MT, Jermendi E, Laporte MA, Lutterodt HE, Annan RA, Barboza M, Amare E, Srichamnong W, Jaramillo-Botero A, Kennedy G, Bertoldo J, Prenni JE, Rajasekharan M, de la Parra J, Ahmed S.   +20 more
europepmc   +1 more source

Toward Fairness in Data Sharing

New England Journal of Medicine, 2016
P J, Devereaux, Gordon, Guyatt, Hertzel, Gerstein, Stuart, Connolly, Salim, Yusuf   +4 more
openaire   +2 more sources

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Enhancing mental health outcomes through a theory of change: supporting open-source data science platforms to promote FAIR data and evidence-based decisions. [PDF]

BMC Health Serv Res
Mugotitsa B, Andeso P, Owoko H, Momanyi R, Mailosi D, Ssebunnya J, Tsofa B, Greenfield J, Kiragga A, Todd J, INSPIRE network.   +10 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

FAIR data management: a framework for fostering data literacy in biomedical sciences education. [PDF]

BMC Med Res Methodol
Gonzalez Soltero R, Pino García D, Bellido A, Ryan P, Rodríguez-Learte AI.   +4 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Data models to GO-FAIR [PDF]

Nature Genetics, 2017
openaire   +2 more sources