Results 91 to 100 of about 3,690,597 (318)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Distributive Justice and The Problem of Friendship [PDF]
, 2014 ArticleFriendship distributes critical benefits across society and does so unequally. Income, levels of education and health vary dramatically according to the quality of individuals' friendships.
Chiara, Cordelli
core +1 more source
Algorithmic Fairness from a Non-ideal Perspective [PDF]
, 2020 Inspired by recent breakthroughs in predictive modeling, practitioners in both industry and government have turned to machine learning with hopes of operationalizing predictions to drive automated decisions.
Dwork Cynthia +5 more
core +2 more sources
The CARE Principles for Indigenous Data Governance
Data Science Journal, 2020 Concerns about secondary use of data and limited opportunities for benefit-sharing have focused attention on the tension that Indigenous communities feel between (1) protecting Indigenous rights and interests in Indigenous data (including traditional ...
Stephanie Russo Carroll +13 more
doaj +1 more source
The FAIR Principles: First Generation Implementation Choices and Challenges
Data Intelligence, 2020 1Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands 2GO FAIR International Support & Coordination Office (GFISCO), Leiden, The Netherlands 3National Science Library, Chinese Academy of Sciences, Beijing 100093, China 4School of Economics ...
B. Mons +3 more
semanticscholar +1 more source
FAIR Principles for Research Software (FAIR4RS Principles)
, 2021 Research software is a fundamental and vital part of research worldwide, yet there remain significant challenges to software productivity, quality, reproducibility, and sustainability. Improving the practice of scholarship is a common goal of the open science, open source software and FAIR (Findable, Accessible, Interoperable and Reusable) communities,
Chue Hong, Neil P. +68 more
openaire +3 more sources
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
FEBS Open Bio, EarlyView.Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
Code of Best Practices in Fair Use for Media Literacy Education [PDF]
, 2008 Outlines five principles representing the consensus among media literacy educators on best practices in fair use -- the right to use copyrighted material without permission or payment when used mainly for cultural or social ...
core
Understanding FAIR Data Principles
, 2021 {"references": ["ACM SIGMOD. (2021). SIGMOD Reproducibility. https://reproducibility.sigmod.org/.", "ANDS (n.d. -a). Australian National Data Service. Data provenance. https://tinyurl.com/yjpgywsp.", "ANDS. (n.d. -b). Australian National Data Service. FAIR data training. https://tinyurl.com/y93k7jpo.", "ANDS. (n.d. -c). Australian National Data Service.
openaire +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source