Results 81 to 90 of about 110,412 (287)

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Introduction to the FAIR principles | FAIR Aware tool

open access: yes, 2023
The EUR Data Coffee Breaks is a 30min session focused on a specific topic.
Guzman-Ramirez, Liz   +2 more
openaire   +2 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

FAIR principles of health sciences research data management

open access: yesRevista Información Científica, 2022
Introduction: Open data for the validation and generalization of research results as well as the recycling of datasets is a felt need in healthcare. Objective: to describe the FAIR principles for research data management. Method: a search in the Scopus,
Eveline García-Espinosa   +3 more
doaj  

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Pacific Coast Committee on American Principles and Fair Play, [draft]

open access: yes, 1943
Document endorsing U.S. government policies including segregation of "disloyal persons of Japanese ancestry," protecting the rights of Japanese Americans to serve in the military, the ability for Japanese Americans to resettle in a way that meets the ...
Pacific Coast Committee on American Principles and Fair Play: author
core  

Common Minimum Metadata for FAIR Semantic Artefacts

open access: yes, 2023
International audienceSemantic interoperability is crucial for the FAIR Principles and strongly relies on Semantic Artefacts that also need to be FAIR. To achieve this, semantic artefacts require rich, structured, and interoperable metadata.
Jonquet, Clement   +4 more
core   +1 more source

Adapting FAIR Evaluation to Photon and Neutron Facilities

open access: yesInternational Journal of Digital Curation
The FAIR principles have become essential in establishing transparent and trustworthy research practices. However the FAIR principles are guidelines indicating the features expected for data to be FAIR, and do not stipulate evaluation criteria ...
Simon Lambert   +2 more
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

Introduction to FAIR Principles

open access: yesWinter School 2 Research data management and policies in Research Performing Organizations and Research Infrastructures, RItrainPlus training programme
Slides of the lecture "Introduction to FAIR principles" for the Winter School 2 dedicated to research data management and policies in Research Performing Organizations and Research Infrastructures in the context of the RItrainPlus training programme designed for students to introduce them to the professional role of managers and operator in a Research ...
openaire   +5 more sources

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