Results 81 to 90 of about 110,519 (287)
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
FAIR Data Maturity Model. Specification and Guidelines [PDF]
, 2020 Findability, Accessibility, Interoperability and Reusability – the FAIR principles – intend to define a minimal set of related but independent and separable guiding principles and practices that enable both machines and humans to find, access ...
FAIR Data Maturity Model Working Group
core +1 more source
State of the Data: Assessing the FAIRness of US Geological Survey Data
Data Science JournalIn response to recent shifts towards open science that emphasize transparency, reproducibility, and access to research data, the US Geological Survey (USGS) conducted a study to assess the degree to which USGS data assets meet the FAIR data principles ...
Vivian B. Hutchison +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
Fair Trial and the Principles Governing It Internationally and Domestically Focusing on Governmental Discretionary Punishment [PDF]
پژوهشنامۀ انتقادی متون و برنامههای علوم انسانی, 2018 The two terms "fair trial" and "statecraft and the principles of justice" were taken in the same sense and have been used interchangeably. No one should be deprived of his life, liberty, and property without a fair trial.
Ahmad Asadian, Jahanbakhsh Salariyan
doaj
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
The rise and stall of a fair trade pioneer: The Cafedirect story [PDF]
, 2010 This is a case study investigating the growth of fair trade pioneer, Cafédirect. We explore the growth of the company and develop strategic insights on how Cafédirect has attained its prominent position in the UK mainstream coffee industry based on ...
Davies, Iain A. +5 more
core +1 more source
How are we FAIR-ing? Creating a FAIR self-assessment checklist for data repositories
IASSIST QuarterlyIn 2023, a team from a local grant-funded medical data repository requested guidance from Penn Libraries on evaluating the extent to which their repository was FAIR-enabling.
Lauren Phegley, Lynda Kellam
doaj +1 more source
The CARE Principles for Indigenous Data Governance
Data Science Journal, 2020 Concerns about secondary use of data and limited opportunities for benefit-sharing have focused attention on the tension that Indigenous communities feel between (1) protecting Indigenous rights and interests in Indigenous data (including traditional ...
Stephanie Russo Carroll +13 more
doaj +1 more source