Results 61 to 70 of about 1,341,301 (290)

FAIR Data Austria – Paving the Way for Enhanced Research Data Management and Collaboration

Zeitschrift für Hochschulentwicklung, 2023
In an age dominated by digital information, the importance of accessible and well-managed research data cannot be overstated. The FAIR Data Austria project is at the forefront of pioneering initiatives that cultivate a culture of data sharing and ...
Alexander Bardel, Ilire Hasani-Mavriqi
doaj   +1 more source

Enhancing reuse of data and biological material in medical research : from FAIR to FAIR-Health [PDF]

, 2018
The known challenge of underutilization of data and biological material from biorepositories as potential resources formedical research has been the focus of discussion for over a decade. Recently developed guidelines for improved data availability and
Casati, Sara, Dagher, Georges, Gabriele, Anton, Holub, Petr, Kohlmayer, Florian, Koumakis, Lefteris, Kozera, Łukasz, Lavitrano, Marialuisa, Litton, Jan-Eric, Martin, Gillian M., Mendy, Maimuna, Ommen, GertJan B. van, Prasser, Fabian, Schlunder, Irene, Sezerman, Osman Ugur, Strapagiel, Dominik, Th. Mayrhofer, Michaela, Valik, Dalibor, Wutte, Andrea, Zanetti, Gianluigi, Zatloukal, Kurt   +20 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

FAIRifying a scholarly publishing service: Methodology based on the OpenEdition’s internal FAIR audit

Journal of Electronic Publishing, 2022
The FAIR principles (Findability, Accessibility, Interoperability, and Reusability) constitute a guide whose aim is to improve the management of digital scholarly resources.
Arnaud Gingold, Karla Avanço
doaj   +2 more sources

FAIR Principles and Zenodo

, 2023
Presentation about FAIR principles and Zenodo.
Kirwan, Luke, Hackstock, Philip
openaire   +1 more source

AI Fairness: from Principles to Practice

, 2022
21 pages, 5 ...
Bateni, Arash, Chan, Matthew, Eitel-Porter, Ray   +2 more
openaire   +3 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Ten quick tips for building FAIR workflows.

PLoS Computational Biology, 2023
Research data is accumulating rapidly and with it the challenge of fully reproducible science. As a consequence, implementation of high-quality management of scientific data has become a global priority.
Casper de Visser, Lennart F Johansson, Purva Kulkarni, Hailiang Mei, Pieter Neerincx, K Joeri van der Velde, Péter Horvatovich, Alain J van Gool, Morris A Swertz, Peter A C 't Hoen, Anna Niehues   +10 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source