Results 71 to 80 of about 94,617 (292)
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul+11 more
wiley +1 more source
The purpose of this study is to examine the constitutional status of the right to proof, as well as its prevalence in relation to infra-constitutional legislation, especially in view of the procedural norms of preclusion.
Fernando Rubin, Gustavo Mascarello Silva
doaj +1 more source
Articles 14 and 15 in ICCPR provide fair trial rights. The 16 concrete guarantees of fair trial rights are usually classified into three parts: basic rules, minimum guarantees and other provisions. A proceeding complying by those concrete guarantees can not necessarily accord with the requirement of fair trial rights, because article 14, paragraph 1 ...
openaire +2 more sources
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon+13 more
wiley +1 more source
Nonostante le varie controversie che circondano il concetto di “giustizia”, quando si parla di una “decisione giusta”, il concetto può essere ridotto a schemi razionali e abbastanza controllabili sul suo significato.
Michele Taruffo
doaj
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez+5 more
wiley +1 more source
The Legacy of Cambodia’s Hybrid Court: Promoting Fair Trial Rights?
The mandate of the Extraordinary Chambers in the Courts of Cambodia (ECCC) concluded in 2022, marking the end of its nearly two-decade presence in Cambodia.
Somaly Kum
doaj +1 more source
THE RIGHT TO A FAIR TRIAL IN THE DYNAMIC INTERPRETATION OF THE EUROPEAN COURT OF HUMAN RIGHTS [PDF]
The European Court of Human Rights has constantly highlighted the importance of Article 6 of the Convention and by a dynamic interpretation, the jurisprudence of the Strasbourg Court has gradually enriched the content and the practical impact of the ...
Alexandra PANAIT
doaj
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella+18 more
wiley +1 more source
Inequalities and Fairness in Cluster Trials
Cluster randomized controlled trials (cluster RCTs) randomize whole clusters of individuals in testing two or more competing interventions. Here we will present the ethical problems raised by cluster RCTs concerning their effect on inequality. We argue that some inequalities generated by cluster RCTs are larger in scope than those generated from ...
Sarah J. L. Edwards, Erin C. Conrad
openaire +2 more sources