Results 71 to 80 of about 3,110,326 (313)
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
QUASI-PERMUTATION REPRESENTATIONS OF METACYCLIC 2-GROUPS [PDF]
Journal of Sciences, Islamic Republic of Iran, 1998 By a quasi-permutation matrix we mean a square matrix over the complex field C with non-negative integral trace. Thus, every permutation matrix over C is a quasipermutation matrix.
doaj
Faithful Uniformly Continuous Representations of Lie Groups [PDF]
Journal of the London Mathematical Society, 1994 Let \(G\) be a connected Lie group. The main result is the equivalence between the following 5 statements: (i) \(G\) is linear, i.e. \(G\) embeds continuously into \(GL_ n(\mathbb{C})\) for \(n\) big enough; (ii) the continuous algebra seminorms separate the points of \({\mathcal E}'(G)\) (the convolution algebra of compactly supported distributions on
Luminet, Denis, Valette, Alain
openaire +2 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Representation, Interpretation, and Surrogative Reasoning [PDF]
, 2007 In this paper, I develop Mauricio Suárez’s distinction between denotation, epistemic representation, and faithful epistemic representation. I then outline an interpretational account of epistemic representation, according to which a vehicle represents a ...
Contessa, Gabriele
core
Brouwer degree, equivariant maps and tensor powers
Abstract and Applied Analysis, 1998 A construction of equivariant maps based on factorization through symmetric powers of a faithful representation is presented together with several examples of related equivariant maps. Applications to differential equations are also discussed.
Z. Balanov +2 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source