Results 201 to 210 of about 219,223 (326)

Mechanical Stimuli‐Induced Manipulation of Malignant Behavior in Bioprinted Cancer Microtissues via PI3K/NF‐κB Activation

Advanced Science, Volume 13, Issue 16, 18 March 2026.
A mechanically tunable ECM platform is created by integrating dECM–alginate matrices with in‐bath tumor printing. The mechanically tunable ECM environment drives tumors to acquire hypoxia, mechanotransduction signaling, metastatic traits, and drug‐resistant phenotypes that collectively promote malignant transformation.
Seok‐Hyeon Lee, Jeongho Lee, Min‐Seo Choi, Minjun Ahn, Sik Yoon, Dongjun Lee, Sae‐Ock Oh, Won‐Woo Cho, Byoung Soo Kim   +8 more
wiley   +1 more source

Melatonin inhibits FAK signaling to suppress PD-L1 expression and enhance chemosensitivity in triple-negative breast cancer. [PDF]

Int J Med Sci
Wu CC, Yang PF, Chang SJ, Pan MR, Li CL, Wu CC, Kan JY, Chen FM, Hou MF, Luo CW.   +9 more
europepmc   +1 more source

Mitophagy and Ubiquitination Coordinate Context‐Specific Mitochondrial Quality Control and EMT/MET Plasticity to Drive Cancer Cell Invasion

Advanced Science, Volume 13, Issue 16, 18 March 2026.
Metastatic invasion emerges when tumor‐intrinsic programs and microenvironmental forces converge on mitochondrial quality control. A context‐stratified framework links mtROS, mtDNA integrity, mechanics and nutrient/oxygen cues to fission–fusion remodeling, mtUPR and mitophagy.
Bin‐Hsu Mao, Bo‐Kai Su, Ying‐Jan Wang, Ting‐Yuan Tu   +3 more
wiley   +1 more source

Eukaryote initiation factor 6 modulates small-cell lung carcinoma plasticity via the integrin-FAK signaling axis. [PDF]

Nat Commun
Peng H, Wang Z, Wang M, Ding Z, Li K, Wang Y, Yu X, Song S, Deng Y, Liu Y, Pu Q, Li L, Cerezo M, Wang W, Liu L, Shen S.   +15 more
europepmc   +1 more source

Phosphorylated-FAK Y397 [PDF]

, 2020
openaire   +1 more source

Neuregulin induces prostate cancer cell migration via HER3/HER2-FAK/Src signaling axis. [PDF]

Cancer Cell Int
Lim EJ, Yoon YJ, Kim Y, Moon HH, Choi YH, Kim YH.   +5 more
europepmc   +1 more source

Bioprinted Excitable Tissues with Multistimulation Systems for Promoting Function and Maturation

Advanced NanoBiomed Research, Volume 6, Issue 3, March 2026.
This review provides an overview of stimulation strategies used to enhance the functional maturation of bioprinted excitable tissues. It addresses key limitations in physiological performance of bioprinted excitable tissues, outlines major stimulation modalities—including electrical, mechanical, optical, magnetic, ultrasound, and hybrid—and examines ...
Uijung Yong, Jinseon Park, Jinah Jang
wiley   +1 more source

Inhibition of focal adhesion kinase impairs tumor formation and preserves hearing in a murine model of NF2-related schwannomatosis. [PDF]

Sci Adv
Mitchell DK, Brewster K, Jiang L, Mang H, Bessler WK, Li X, Lu Q, Qian S, York E, Morrow SK, Dixon SAH, Davis C, Chan KK, Smith A, Flint AC, Le VV, Geisinger A, Enane F, Nabet B, Rhodes SD, Angus SP, Clapp DW.   +21 more
europepmc   +1 more source

FAK and HAS Inhibition Synergistically Decrease Colon Cancer Cell Viability and Affect Expression of Critical Genes

, 2013
Melissa Heffler, Vita Golubovskaya, Jeffrey M. Conroy, Song Liu, Dan Wang, William G. Cance, Kelli Bullard Dunn   +6 more
openalex   +2 more sources

FAK Inhibitor GSK2256098 [PDF]

, 2020
openaire   +1 more source