Loss of ROR2 Tyrosine Kinase Receptor Is Associated With Endothelial Dysfunction in PAH via Inappropriate Integrin β1 Activation. [PDF]
Mitra A +22 more
europepmc +1 more source
A Novel Model System to Identify Cellular and Molecular Defects Underlying Rare Genetic Disorders
ABSTRACT Ankyloblepharon‐ectodermal defects‐cleft lip/palate (AEC) is a disorder caused by autosomal‐dominant mutations in the TP63 gene. AEC is characterised by the presence of severe and painful skin erosions that can take years to heal. Current treatment options for these devastating lesions are limited, highlighting the need for new therapeutic ...
Maddison N. Salois +4 more
wiley +1 more source
Cyclin D1/D2-CDK4 Drives Cell Migration by Orchestrating Cytoskeletal Dynamics Through a TGFβ-FAK-Rac1 Axis. [PDF]
Guo R +5 more
europepmc +1 more source
αvβ5 Integrin/FAK/PGC-1α Pathway Confers Protective Effects on Retinal Pigment Epithelium
Murilo Felix Roggia, Takashi Ueta
openalex +1 more source
Abstract Nonfunctioning pituitary adenomas (NFPAs) are common intracranial tumors that, despite being histologically benign, can exhibit invasive growth, as well as postoperative tumor progression. Surgical resection is the primary treatment of choice; however, residual tumor tissue is frequently observed, with between 30% and 50% of these cases ...
Thomas Skoglund +5 more
wiley +1 more source
Correction: Golubovskaya et al. Gene Expression Profiling Identifies Important Genes Affected by R2 Compound Disrupting FAK and P53 Complex. <i>Cancers</i> 2014, <i>6</i>, 166-178. [PDF]
Golubovskaya VM +5 more
europepmc +1 more source
Increased expression of FAK isoforms as potential cancer biomarkers in ovarian cancer
Manuel Nolasco‐Quiroga +10 more
openalex +2 more sources
The Association of Acne Vulgaris and Disease Severity With Serum Amyloid A1 and Insulin Levels
ABSTRACT Background Acne vulgaris is a chronic inflammatory disease involving multiple factors such as increased sebum production, follicular hyperkeratinization, microbial colonization, and inflammation. Serum amyloid A1 (SAA1), an acute phase protein, and insulin, a hormone linked to metabolic and inflammatory pathways, may play significant roles in ...
Pelin Hizli +4 more
wiley +1 more source

