Results 281 to 290 of about 219,223 (326)

FAK Inhibitor PF-00562271 [PDF]

, 2020
openaire   +1 more source

Genetic deletion of ASIC3 alters left ventricular remodeling and autonomic function after myocardial infarction in mice

Physiological Reports, Volume 14, Issue 5, March 2026.
Abstract Cardiac afferent neurons have been shown to trigger overactivation of neurohormonal systems known to drive adverse cardiac remodeling following myocardial infarction (MI). Acid‐sensing ion channels (ASICs) that are highly expressed in cardiac sympathetic afferents sense ischemia‐induced myocardial acidosis.
Karley M. Monaghan, David D. Gibbons, Chad C. Ward, Maram El‐Geneidy, William J. Kutschke, Kathy A. Zimmerman, Donald A. Morgan, Harald M. Stauss, Anne Marie S. Harding, Michelle C. M. Bader, Peter M. Snyder, Rasna Sabharwal, Robert M. Weiss, Kamal Rahmouni, Christopher J. Benson   +14 more
wiley   +1 more source

Enhanced ADP-heptose-dependent NF-κB activation by Helicobacter pylori CagA through cortactin-Src-dependent tyrosine phosphorylation of IKKβ. [PDF]

Microlife
Sharafutdinov I, Tegtmeyer N, Friedrich B, Naumann M, Backert S.   +4 more
europepmc   +1 more source

Magnetic chitosan nanoparticle-exosome hydrogel enhances bladder function in diabetic bladder dysfunction via activating the FAK-p38 MAPK-GATA4 axis in adipose-derived mesenchymal stromal cells. [PDF]

Regen Biomater
Zheng J, Zhang D, Li H, Jin R, Chen H, Sun X, Zhang H.   +6 more
europepmc   +1 more source

Integrative bulk and single-cell transcriptomic analysis reveals COL1A2-driven ECM remodeling and focal adhesion signaling associated with the transition from non-muscle-invasive to muscle-invasive bladder cancer. [PDF]

Front Oncol
Li M, Liu X, Xue Y, Lu Y, Chen Z, Zhang Y, Chen W, Zhao SC, Wang K, Feng N.   +9 more
europepmc   +1 more source

Cancer-associated fibroblasts (CAFs) derived from MFAP2 promote CRC proliferation and metastasis while suppressing CD8⁺ T cell-mediated antitumor immunity. [PDF]

Cell Death Dis
Zhang X, Fei Y, Xie C, Li T, Niu B, Yang Z, Song M, Meng F, Diao H, Ji J, Du Q, Liu C.   +11 more
europepmc   +1 more source

Activation of SV2B Inhibits Matrix-Stiffness-Induced Tumorigenesis and EMT in Glioma via FAK/PI3K/AKT Signaling Pathway. [PDF]

Oncol Ther
Ma D, Wang Y, Sang L, Gao T.
europepmc   +1 more source

RhoE downregulation leads to enhanced cholesterol biosynthesis and sorafenib resistance in hepatocellular carcinoma. [PDF]

J Biol Chem
Feng J, Ye L, Chen C, Zhu Y, Liu R, Yu H, Lu L, Gong K, Li W.   +8 more
europepmc   +1 more source

The stress-activated kinase p38 mediates non-canonical activation of Src and tyrosine phosphorylation of the adapter protein TAB1. [PDF]

J Biol Chem
Onuma I, Iwata Y, Zhou Y, Nakada M, Kondo A, Iwahara H, Natori K, Yokoyama S, Chihara K, Takeuchi K, Sada K, Ozawa T, Mizuguchi M, Yamagishi N, Kracht M, Sakurai H.   +15 more
europepmc   +1 more source