Results 71 to 80 of about 5,447,969 (268)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

LazerLab/twitter-fake-news-replication: Public Replication Package for Fake news on Twitter

open access: yes, 2019
Repository for public code and data associated with the paper "Fake News on Twitter During the 2016 U.S.
Lisa Friedland, Kenny Joseph
core   +1 more source

Fake News Detection using ML

open access: yes, 2021
This Project “Fake News Detection”  works on the  applications of Natural Language Processing(NLP) techniques that recognizes the \u27fake news\u27, that is deceptive news stories which comes from the unidentified sources.During this systematic
et. al., Dr.Jayakumar V,
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Digital revolution and fake news [PDF]

open access: yes, 2017
HE digital revolution and its instantaneous short-term benefits have been celebrated and sold to mankind by peddlers of technology as a blessing in our march towards greater efficiency and productivity. This, it is argued, will fulfil our increasing lust
Ahmad Farouk, Azeem Fazwan
core   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

An In-Depth Comparative Analysis of Fake News Detection Approaches in Social Media: Methodologies, Challenges, and Future Directions [PDF]

open access: yesInternational Journal of Information and Communication Technology Research
The proliferation of fake news on social networks poses significant challenges for trust, security, and societal well-being. In this paper, we present a comprehensive study of fake news detection approaches and techniques, introducing a novel framework ...
Tala Tafazzoli, Abouzar Arab Sorkhi
doaj  

An Efficient Fake News Detection System Using Contextualized Embeddings and Recurrent Neural Network.

open access: yesInternational Journal of Interactive Multimedia and Artificial Intelligence
Fake news is detrimental for society and individuals. Since the information dissipation through online media is too quick, an efficient system is needed to detect and counter the propagation of fake news on social media. Many studies have been performed
Junaid Ali Reshi, Rashid Ali
doaj   +1 more source

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