Results 41 to 50 of about 3,131,355 (307)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Evaluation of older people\u27s knowledge, awareness, motivation and perceptions about falls and falls prevention in residential aged care homes: A tale of two cities [PDF]
, 2018 Falls prevention strategies can only be effective in reducing falls amongst older people if they are adopted and enacted in their daily lives. There is limited evidence identifying what older people in residential aged care (RAC) homes understand about ...
Anderson, Michelle +9 more
core +1 more source
Implementation of Post Falls Huddles in Skilled Nursing Facility [PDF]
, 2020 The purpose of this paper is to discuss the quality improvement project, implementation of the post fall huddle in a long-term care facility. Falls are the most common problem in adults 65 years and older.
Lomax, Princess
core +1 more source
Adult Astrogenesis and the Etiology of Cortical Neurodegeneration
Journal of Experimental Neuroscience, 2015 As more evidence points to a clear role for astrocytes in synaptic processing, synaptogenesis and cognition, continuing research on astrocytic function could lead to strategies for neurodegenerative disease prevention.
Tal C. Mohn, Andrew O. Koob
doaj +1 more source
IDCases, 2017 Pasteurella multocida is a gram-negative organism that commonly colonizes the mouth of cats and dogs, and is known to cause infection in humans associated with animal bites or scratches.
Joel T. Costanzo, II +2 more
doaj +1 more source
Cybersecurity Resilience Demonstration for Wind Energy Sites in Co-Simulation Environment
IEEE Access, 2023 Sandia National Laboratories and Idaho National Laboratory deployed state-of-the-art cybersecurity technologies within a virtualized, cyber-physical wind energy site to demonstrate their impact on security and resilience. This work was designed to better
Michael Mccarty +10 more
doaj +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Arquitecturas del Sur, 2016 El centro histórico de Camagüey, declarado Patrimonio Cultural de la Humanidad en 2008, atesora un número considerable de edificios correspondientes al Movimiento Moderno, construidos en la década de 1950, que sufren actualmente modificaciones para ...
Dianelis Falls Valdivieso
doaj
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
The Association between Sleep Problems, Sleep Medication Use, and Falls in Community-Dwelling Older Adults: Results from the Health and Retirement Study 2010 [PDF]
, 2016 Background. Very few studies have assessed the impact of poor sleep and sleep medication use on the risk of falls among community-dwelling older adults. The objective of this study was to evaluate the association between sleep problems, sleep medication ...
Min, Yaena +2 more
core +3 more sources