Results 51 to 60 of about 6,203,398 (300)

THE PUZZLE OF THE FALSE POSITVE REACTIONS IN CR. NEOFORMANSE’S CAPSULAR ANTIGEN SLIDE LATES AGGLUTINATION TEST BY SERA OF PATIENTS WITH RHEUMATOID ARTHRITIS [PDF]

open access: yesIranian Journal of Public Health, 1987
Different examination have shown that rheumatoid factor is not responsible for false positive reaction (F.P.R.) in Cr. Neoformanse’s free capsular antigen latex agglutination test, whereas high levels of iron in sera of patients with rheumatoid arthritis
F. Zaini   +1 more
doaj   +1 more source

False positivity of non-targeted infections in malaria rapid diagnostic tests: the case of human african trypanosomiasis. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2013
BACKGROUND: In endemic settings, diagnosis of malaria increasingly relies on the use of rapid diagnostic tests (RDTs). False positivity of such RDTs is poorly documented, although it is especially relevant in those infections that resemble malaria, such ...
Philippe Gillet   +8 more
doaj   +1 more source

High-throughput Plasmodium falciparum hrp2 and hrp3 gene deletion typing by digital PCR to monitor malaria rapid diagnostic test efficacy

open access: yeseLife, 2022
Most rapid diagnostic tests for Plasmodium falciparum malaria target the Histidine-Rich Proteins 2 and 3 (HRP2 and HRP3). Deletions of the hrp2 and hrp3 genes result in false-negative tests and are a threat for malaria control.
Claudia A Vera-Arias   +17 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

False negative polymerase chain reaction on cerebrospinal fluid samples in tuberculous meningitis established by culture [PDF]

open access: yesJournal of Neurology, Neurosurgery & Psychiatry, 1999
The polymerase chain reaction (PCR) has been reported to be of diagnostic value when performed on CSF samples in tuberculous meningitis.1-4 Rapid amplification of Mycobacteruim tuberculosis specific DNA enables results to be available within 48 hours and can influence treatment decisions.
M MELZER   +4 more
openaire   +1 more source

Definitions of true-positive, false-positive, true-negative and false-negative used in our study.

open access: yes, 2016
Definitions of true-positive, false-positive, true-negative and false-negative used in our study.
Lotte M. G. Steuten (838598)   +5 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Radiologic–Pathologic Discordance After Image-Guided Breast Biopsy: A Systematic Review of Prevalence and Outcomes

open access: yesMedical Sciences
Background: Radiologic–pathologic discordance remains an important concern owing to the absence of standardized guidelines. This systematic review aimed to summarize the prevalence of discordant benign outcomes, defined as suspicious imaging findings ...
Pirada Yincharoen   +2 more
doaj   +1 more source

True positive and false negative rate.

open access: yes, 2022
True positive and false negative rate.
Rois Muqsith Fatawy (12859104)   +30 more
core   +1 more source

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