Results 61 to 70 of about 6,203,398 (300)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Fabrication of a Microfluidic Test Device with a 3D Printer and Its Combination with the Loop Mediated Isothermal Amplification Method to Detect Streptococcus pyogenes

Micromachines
New rapid, reliable, and cost-effective alternative systems are needed for the rapid diagnosis of Streptococcus pyogenes. The aim of this study was to fabricate a microfluidic test device to detect Streptococcus pyogenes by combining the Loop-mediated ...
Hayriye Kirkoyun Uysal, Meltem Eryildiz, Mehmet Demirci   +2 more
doaj   +1 more source

Strategy for Controlling Preferential Amplification and Avoiding False Negatives in PCR Typing

BioTechniques, 1996
The use of the PCR method for routine testing has increased dramatically during recent years. Most assays involve coamplification either of an internal control, of several alleles at a given locus or of a variety of bands produced by low-stringency ...
Thomas Weissensteiner, Jerry S. Lanchbury   +1 more
doaj   +1 more source

True positive (TP), true negative (TN), false positive (FP) and false negative (FN) in US and MRI.

, 2022
True positive (TP), true negative (TN), false positive (FP) and false negative (FN) in US and MRI.
Mee Hoong See (12253146), Farhana Fadzli (797895), Nur Aishah Mohd Taib (12090811), Wai Yee Chan (9191150), Marlina Tanty Ramli Hamid (13977663), Mohammad Nazri Md Shah (13977666), Kartini Rahmat (2153977), Shaleen Kaur (13977669), Wai Keong Cheah (13977660)   +8 more
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Contrastive sentence representation learning with adaptive false negative cancellation [PDF]

Contrastive sentence representation learning has made great progress thanks to a range of text augmentation strategies and hard negative sampling techniques.
Lingling Xu, Fu Lee Wang, Xu, Lingling, Li, Qing, Weiming Wang, Tao, Xiaohui, Wang, Weiming, Xiaohui Tao, Xie, Haoran, Haoran Xie, Qing Li, Wang, Fu Lee   +11 more
core   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

PECULIARITIES OF CONTROL OF HUMAN ALBUMIN DRUGS ON THE CONTENT OF BACTERIAL ENDOTOXINS

Разработка и регистрация лекарственных средств, 2019
The problem was considered to determine bacterial endotoxins in human albumin drugs. To improve the safety of medicines the option of dual control was recommended, which includes the rabbit pyrogen test and determining bacterial endotoxins by the LAL ...
T. V. Kukunina, A. G. Israfilov, M. L. Romanenkova, R. S. Gaynullina, L. G. Fedko   +4 more
doaj  

Influence of visual field results in the glaucoma diagnosis

Revista Brasileira de Oftalmologia
Objective: To determine the influence of visual field results in the diagnosis of glaucoma. Methods: A questionnaire with ophthalmologists was conducted where slides of a digital photograph of the optic disc and computerized visual field exam were ...
Leopoldo Magacho, Cláudia Gomide Vilela de Sousa Franco, Gustavo de Paula Figueiredo, Arnaldo Machado Borges do Vale, Bruna Thomé Rassi, Marcos P. Ávila   +5 more
doaj   +1 more source

The effects of intranasal oxytocin on black participants’ responses to outgroup acceptance and rejection

Frontiers in Psychology, 2022
Social acceptance (vs. rejection) is assumed to have widespread positive effects on the recipient; however, ethnic/racial minorities often react negatively to social acceptance by White individuals.
Jiyoung Park, Joshua Woolley, Wendy Berry Mendes   +2 more
doaj   +1 more source