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Evaluation of false positive and false negative errors in targeted next generation sequencing [PDF]

open access: yesGenome Biology
Background Next-generation sequencing (NGS) has become an indispensable diagnostic tool across various diseases. However, sequencing and analysis errors remain major barriers to clinical implementation.
Youngbeen Moon   +10 more
doaj   +2 more sources

FALSE-NEGATIVE DENGUE CASES [PDF]

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 2015
Sim Sai TIN, Viroj WIWANITKIT
doaj   +4 more sources

Understanding False Negative in Prenatal Testing

open access: yesDiagnostics, 2021
A false negative can happen in many kinds of medical tests, regardless of whether they are screening or diagnostic in nature. However, it inevitably poses serious concerns especially in a prenatal setting because its sequelae can mark the birth of an ...
Mark I. Evans, Ming Chen, David W. Britt
doaj   +1 more source

How to Avoid False-Negative and False-Positive COVID-19 PCR Testing

open access: yesInternational Journal of Translational Medicine, 2022
Background: Up to 40% of test results for COVID-19 in the presence of clinical manifestations of the disease might be negative. The reason for a false-negative result might originate from any step of the analysis: poor-quality or empty swab, poor RNA ...
Irina Fevraleva   +3 more
doaj   +1 more source

Cytohistological correlation of thyroid fine-needle aspiration cytology with emphasis on discordant cases: A tertiary care center study

open access: yesIndian Journal of Health Sciences and Biomedical Research KLEU, 2023
CONTEXT: Fine-needle aspiration (FNA) is a reliable, most noninvasive, cheap, and efficient procedure to differentiate between benign and malignant thyroid nodules.[1] The six proposed Bethesda categories are known to reduce the “gray zone” in thyroid ...
G V Neethu   +3 more
doaj   +1 more source

Reasons for truly negative cytology reports preceding the diagnoses of invasive cervical cancer—Results of a false‐negative cytology audit in Polish Cervical Cancer Screening Programme

open access: yesCancer Medicine, 2023
Background False‐negative (FN) results in cervical cancer (CC) screening pose significant risk for participants and should be audited. The aim of the study was to analyse the results of audit of FN slides collected in 2010–2013 in Polish Cervical Cancer ...
Anna Macios   +2 more
doaj   +1 more source

Assessment of Health Monitoring Trustworthiness of Avionics Systems

open access: yesInternational Journal of Prognostics and Health Management, 2021
The article provides a methodology for assessing the trustworthiness of health monitoring the dismounted avionics systems with automated test equipment (ATE).
Vladimir Ulansky   +2 more
doaj   +1 more source

Critical Congenital Heart Disease Detection in the Screening Era: Do Not Neglect the Examination!

open access: yesAmerican Journal of Perinatology Reports, 2021
Pulse oximetry oxygen saturation (SpO2)-based critical congenital heart disease (CCHD) screening is effective in detection of cyanotic heart lesions.
Deepika Sankaran   +4 more
doaj   +1 more source

Prediction of cytology–histology discrepancy when Bethesda cytology reports benign results for thyroid nodules in women: with special emphasis on pregnancy

open access: yesLibyan Journal of Medicine, 2023
Objectives: Benign category of Bethesda classification is generally well known to carry a false-negative rate of 0–3%. The current study was designed to investigate the rate of false-negative cytology in patients who underwent thyroidectomy for ...
Aysun Firat, Ethem Unal
doaj   +1 more source

Accurate Interpretation of SARS-CoV-2 Antigen Detection by Immunochromatography

open access: yesFrontiers in Medicine, 2022
SARS-CoV-2 is a serious infectious respiratory virus that can cause lung, heart, kidney, and liver damage and even cause death. Early diagnosis of SARS-CoV-2 infection is vital for epidemic prevention and control.
Wenxia Shao
doaj   +1 more source

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