Results 231 to 240 of about 537,139 (296)

Reframing Eczema: Th2-Skewed Contact Sensitization, Atopy Patch Testing, and Systemic Contact Dermatitis. [PDF]

Curr Allergy Asthma Rep
Jacob SE, Scheman A, Nedorost S.
europepmc   +1 more source

A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity

Advanced Science, EarlyView.
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu, Xinyu Sun, Wanxia Ma, Jianming Yang, Xuan Sun, Lisong Zhang, Yumeng Liu, Tianshu Ren, Qi Wang, Jingyu Wang, Xiao Li, Xianping Peng, Liu Yang, Junqiang Lv, Zhi Yao, Zhi‐Song Zhang, Quan Wang   +16 more
wiley   +1 more source

"Screening isn't Your Ticket to Vacation": In-depth Interviews With Women in the United States Who Experienced an Interval Breast Cancer. [PDF]

Cancer Control
Irvin V, Bertoni D, Leon Gutierrez M, Ignacio JC, Hagerty S, Moylan K, Franklin A.   +6 more
europepmc   +1 more source

A NeuroD1 AAV‐Based Gene Therapy for Functional Brain Repair in Alzheimer's Disease‐Like Non‐Human Primate Model

Advanced Science, EarlyView.
This study tests NeuroD1 AAV‐based gene therapy in a non‐human primate Alzheimer's disease model. The therapy prevents neuronal damage, inhibits hippocampal atrophy, and reduces neuroinflammation. It also repairs vascular and blood‐brain barrier damage, restores cerebrospinal fluid biomarkers, enhances hippocampal glucose metabolism, and improves ...
Zhouquan Jiang, Yongpeng Qin, Bin Luo, Fan Bai, Jiangyue Liu, Long Ma, Shu He, Rongjie Chen, Yuchen Wang, Shanggong Liu, Ying Sun, Yi Chen, Shuo Zhang, Jiaqi Liang, Feng Liao, Huiyi Wei, Junjie Wei, Lu Wang, Hao Xu, Zheng Wu, Gong Chen, Wenliang Lei   +21 more
wiley   +1 more source

Rare metabolic gene essentiality is a determinant of microniche adaptation in Eschherichia coli. [PDF]

PLoS Pathog
Ardalani O, Phaneuf PV, Krishnan J, Chauhan SM, Pride D, Zielinski DC, Monk JM, Nielsen LK, Palsson BO.   +8 more
europepmc   +1 more source

Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome

Advanced Science, EarlyView.
By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang, Siqi Guo, Jing Li, Qianqian Huang, Jing Ning, Binbin Xia, Xun Lv, Xiang Liu, Zeyu Gao, Jine Li, Longchao Liu, Moshi Song, Jun Wang   +12 more
wiley   +1 more source

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

Lyophilised colourimetric LAMP for visual readout with dual colour indicators.

Analyst
Malpartida-Cardenas K, Stringer OW, Cavuto ML, Holmes A, Rodriguez-Manzano J.   +4 more
europepmc   +1 more source

Multi-strain analysis of <i>Pseudomonas putida</i> reveals the metabolic and genetic diversity of the species. [PDF]

mSystems
Mueller J, Krishnan J, Wei Q, Hefner Y, Monk JM, Verkler H, Tibocha-Bonilla JD, Ayala A, Palsson BO, Feist AM, Niu W.   +10 more
europepmc   +1 more source

Evaluating the detection capabilities of nanopore sequencing for Borrelia burgdorferi detection in blacklegged ticks. [PDF]

Sci Rep
Cassens J, Kipp EJ, Frank LE, Larsen PA, Oliver JD.   +4 more
europepmc   +1 more source