Results 71 to 80 of about 726,554 (241)

True or false? The contested terrain of false allegations [PDF]

, 2013
This paper aims to contribute to and clarify the debate around false allegations of sexual assault by providing a summary of recent literature, including consideration of the classifications and methods of defining a false allegation, whether there is
Cindy Tarczon, Liz Wall
core  

Distribution of true and false positives and true and false negatives.

, 2017
Distribution of true and false positives and true and false negatives.
Simon J. Greenhill (366401), Russell D. Gray (165685), Johann-Mattis List (3241566)   +2 more
core   +1 more source

Strategy for Controlling Preferential Amplification and Avoiding False Negatives in PCR Typing

BioTechniques, 1996
The use of the PCR method for routine testing has increased dramatically during recent years. Most assays involve coamplification either of an internal control, of several alleles at a given locus or of a variety of bands produced by low-stringency ...
Thomas Weissensteiner, Jerry S. Lanchbury   +1 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Variables associated with the number of true negatives (TN), false negatives (FN), false positives (FP) and true positives (TP), for multiple testing of m null hypotheses.

, 2015
Variables associated with the number of true negatives (TN), false negatives (FN), false positives (FP) and true positives (TP), for multiple testing of m null hypotheses.
Hideki Asoh (5662846), Yuji Takeda (178444), Steven Phillips (171179), Archana K. Singh (715044)   +3 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

False negatives in the Microsoft building footprint data.

, 2022
Examples shown in urban and rural contexts. Locations were chosen based on the presence of false negatives and do not generally reflect the typical proportion of false negative instances around the state. (DOCX)
Nicholas J. Depsky (13047382), Lara Cushing (2914064), Rachel Morello-Frosch (61768)   +2 more
core   +1 more source

Accounting for observation biases associated with counts of young when estimating fecundity: case study on the arboreal-nesting red kite (Milvus milvus)

Peer Community Journal
Counting the number of young in a brood from a distance is common practice, for example in tree-nesting birds. These counts can, however, suffer from over and undercounting, which can lead to biased estimates of fecundity (average number of nestlings per
Sollmann, Rahel, Adenot, Nathalie, Spakovszky, Peter, Windt, Jendrik, Mattsson, Brady J.   +4 more
doaj   +1 more source

High false positives and false negatives in yeast parameter in an automated urine sediment analyzer [PDF]

Journal of Medical Biochemistry, 2015
Background: Automated urine sediment analyzers have proven their feasibility in medical laboratories. However, editing manual microscopic review of some specimens severely limits the usefulness of such systems.
Aydin Ozgur, Yasar Ellidag Hamit, Eren Esin, Yilmaz Necat   +3 more
doaj