Results 41 to 50 of about 6,406,615 (302)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

False-negative and false-positive rates per quarter, April 2012-June 2014.

, 2016
False-negative and false-positive rates per quarter, April 2012-June 2014.
Pedro G. Suarez (2795539), Genetu Alem (3176130), Dereje Habte (235296), Belaineh Girma (95494), Muluken Melese (34781), Yewulsew Kassie (2795530), Gonfa Ayana (466721), Solomon Negash (2795545), Feleke Belachew (3176136), Jemal Seid (3176133), Nebiyu Hiruy (2795551), Yared K. Haile (2795548), Degu Jerene (75554)   +12 more
core   +1 more source

True positive, false positive, false negative for category 1.

, 2023
True positive, false positive, false negative for category 1.
Muddassar Azam Sindhu (8735385), Rabeeh Ayaz Abbasi (12999930), Maryam Imtiaz Malik (16436742)   +2 more
core   +1 more source

EFFECTIVENESS OF TUBERCULOUS RECOMBINANT ALLERGEN SKIN TESTS FOR DETECTING TUBERCULOSIS IN CHILDREN AND ADOLESCENTS OF MOSCOW IN 2013

Педиатрическая фармакология, 2015
Explanation. Mantoux test is used to detect the tuberculous infection; however, low specificity of this method results in a high rate of false positive responses due to cross-reactions of PPD (protein purified derivate) antigens contained in many ...
L. V. Slogotskaya, O. Y. Senchikhina, G. V. Nikitina, E. M. Bogorodskaya   +3 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Clinical characteristics and cause analysis of false-positive results in treponemal testing among patients

Annals of Medicine
Background Currently, there is a dearth of systematic research data on the phenomenon of false-positive reactions in treponemal tests. The aim of this study is to analyze the clinical characteristics and influencing factors associated with false-positive
Wei Wang, Xuzhou Fan, Keyi Zhou, Qianqian Chen, Xuelian Huang   +4 more
doaj   +1 more source

EFFICIENCY OF DIFFERENT TECHNIQUES FOR ANTIBODY DETERMINATION AND TESTING OF ANTIGEN-BINDING LYMPHOCYTES IN DIAGNOSTICS OF BRUCELLOSIS

Медицинская иммунология, 2014
. The aim of this study was to compare the efficiency of different methods applied for the diagnostics of brucellosis. Huddlson and Wright reactions, RoseBengal test, ELISA-based test system (IgG determination), and a test for antigen-binding lymphocytes
B. V. Karalnik, T. G. Denisova, G. B. Zhunusova, S. A. Fedosov, A. A. Zhankin, K. S. Ospanov, S. U. Mizanbaieva   +6 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

True positive, false positive, false negative for category 2.

, 2023
True positive, false positive, false negative for category 2.
Muddassar Azam Sindhu (8735385), Rabeeh Ayaz Abbasi (12999930), Maryam Imtiaz Malik (16436742)   +2 more
core   +1 more source

Weight of evidence approach using a TK gene mutation assay with human TK6 cells for follow-up of positive results in Ames tests: a collaborative study by MMS/JEMS

Genes and Environment, 2021
Background Conflicting results between bacterial mutagenicity tests (the Ames test) and mammalian carcinogenicity tests might be due to species differences in metabolism, genome structure, and DNA repair systems. Mutagenicity assays using human cells are
Manabu Yasui, Takayuki Fukuda, Akiko Ukai, Jiro Maniwa, Tadashi Imamura, Tsuneo Hashizume, Haruna Yamamoto, Kaori Shibuya, Kazunori Narumi, Yohei Fujiishi, Emiko Okada, Saori Fujishima, Mika Yamamoto, Naoko Otani, Maki Nakamura, Ryoichi Nishimura, Maya Ueda, Masayuki Mishima, Kaori Matsuzaki, Akira Takeiri, Kenji Tanaka, Yuki Okada, Munehiro Nakagawa, Shuichi Hamada, Akihiko Kajikawa, Hiroshi Honda, Jun Adachi, Kentaro Misaki, Kumiko Ogawa, Masamitsu Honma   +29 more
doaj   +1 more source