Results 51 to 60 of about 1,640,499 (279)

Effect of false positive and false negative rates on inference of binding target conservation across different conditions and species from ChIP-chip data

BMC Bioinformatics, 2009
Background ChIP-chip data are routinely used to identify transcription factor binding targets. However, the presence of false positives and false negatives in ChIP-chip data complicates and hinders analyses, especially when the binding targets for a ...
Zhao Hongyu, Datta Debayan
doaj   +1 more source

Research on an Intra-Pulse Orthogonal Waveform and Methods Resisting Interrupted-Sampling Repeater Jamming within the Same Frequency Band

Remote Sensing, 2023
Interrupted-sampling repeater jamming (ISRJ) is a kind of intra-pulse coherent deception jamming that can generate false target peaks in the range profile and interfere with the detection and tracking of real targets.
Huahua Dai, Yingxiao Zhao, Hanning Su, Zhuang Wang, Qinglong Bao, Jiameng Pan   +5 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Weak Underwater Acoustic Target Detection and Enhancement with BM-SEED Algorithm

Journal of Marine Science and Engineering, 2023
Bearing time record (BTR) is widely used in the field of passive sonar information processing for target detecting and tracking. One of its challenges is to obtain high-resolution beamforming power spectral to facilitate the directions estimating of ...
Fan Yin, Chao Li, Haibin Wang, Leixin Nie, Yonglin Zhang, Chaonan Liu, Fan Yang   +6 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Age-related increases in false recognition: The role of perceptual and conceptual similarity [PDF]

, 2014
Older adults are more likely to falsely recognize novel events than young adults, and recent behavioral and neuroimaging evidence points to a reduced ability to distinguish overlapping information due to decline in hippocampal pattern separation. However,
Morcom, Alexa, Laura M Pidgeon (16273007), Alexa Morcom (6188726), Morcom, Alexa M., Pidgeon, Laura Marie, Pidgeon, Laura M, Pidgeon, Laura M., Laura M. Pidgeon, Alexa M. Morcom, Morcom, Alexa M   +9 more
core   +1 more source

TFCD-Net: Target and False Alarm Collaborative Detection Network for Infrared Imagery

Remote Sensing
Infrared small target detection (ISTD) plays a crucial role in both civilian and military applications. Detecting small targets against dense cluttered backgrounds remains a challenging task, requiring the collaboration of false alarm source elimination ...
Siying Cao, Zhi Li, Jiakun Deng, Yi’an Huang, Zhenming Peng   +4 more
doaj   +1 more source

LFM Radar Convolution Jamming Suppression Based on Oblique Projection in FrFT Domain

MATEC Web of Conferences, 2016
Convolution false-targets jamming against LFM fire-control radars generates range and velocity false targets which are coherent with target echo, which increases the difficulty of jamming detection and suppression and makes the victim radar system lost ...
Wang Jun, Ping Fulong, Zhao Yuan, Tang Bin   +3 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source