Results 231 to 240 of about 3,303,931 (259)

Hereditary Pancreatic Cancer: Genetic Risk, Surveillance Strategies, and Therapeutic Implications. [PDF]

Int J Mol Sci
Marafioti M, Patruno M, Musarra M, Silvestris N, Portillo Funes JA, Omero F, Sapuppo E, Cianci V, Calabrò M, Irrera N, Briuglia S, Santarpia M, Speranza D.   +12 more
europepmc   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Correction to "Discovering Hereditary Risk Through Surveillance: A Prospective Genetic Analysis of Individuals With Familial Pancreatic Cancer". [PDF]

United European Gastroenterol J
europepmc   +1 more source

Clinical Utility of Germline Whole-Exome Sequencing Beyond Multigene Panels in Hereditary Cancer. [PDF]

Genes (Basel)
Dell'Elice A, Lombardi L, Anaclerio F, Palmarini C, Canale N, Secondi L, Stratta G, Vitali M, Tavoletta MS, Grossi S, Babore A, Milillo C, Dovizio M, Ballerini P, Gatta V, Stuppia L, Antonucci I.   +16 more
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Inhibitory effects of c-MYC degrading rLON protease on intestinal polyps in PIRC rat, a familial adenomatous polyposis model. [PDF]

Neoplasia
Venkatachalam K, Madka V, Pathuri G, Bao A, Stratton N, Singh A, Miller MS, Gunasekharan V, Rao CV.   +8 more
europepmc   +1 more source

PCSK9 rs562556 variant and survival in BRCA1 mutation carriers and mutation-negative familial breast cancer. [PDF]

NPJ Breast Cancer
Cybulski C, Kluźniak W, Wokołorczyk D, Zamani N, Stempa K, Gliniewicz K, Huzarski T, Falco M, Sun P, Gronwald J, Lubiński J, Narod S, Akbari MR.   +12 more
europepmc   +1 more source

A Qualitative Study of Family Centrality in Modified Dignity Therapy Experiences Among Korean Patients With Advanced Cancer: KCSG-PC22-10. [PDF]

J Korean Med Sci
Park SR, Cho M, Jung HY, Shin SH, Cha YJ.   +4 more
europepmc   +1 more source

Correction to "Clinical, genetic, and familial features of POT1 tumor predisposition syndrome". [PDF]

Cancer
europepmc   +1 more source