Results 71 to 80 of about 3,303,931 (259)

Using polygenic risk modification to improve breast cancer prevention: study protocol for the PRiMo multicentre randomised controlled trial

BMJ Open
Introduction Established personal and familial risk factors contribute collectively to a woman’s risk of breast or ovarian cancer. Existing clinical services offer genetic testing for pathogenic variants in high-risk genes to investigate these risks but ...
Melissa C Southey, Georgia Chenevix-Trench, Paul A James, Simone McInerny, Lyon Mascarenhas, Tatiane Yanes, Lara Petelin, Mary-Anne Young   +7 more
doaj   +1 more source

Parents of Youth With Cancer Report on Their Psychosocial Care: iSTEPPP Survey Finds Alignment and Gaps With Standards

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Standards for Psychosocial Care for Children with Cancer and Their Families guide the provision of comprehensive psychosocial care. Parallel to research characterizing implementation of the Standards from the perspective of providers, this study examines implementation of the Standards from the perspective of parents of youth ...
Emily M. Pariseau, Kimberly Buff, Michele A. Scialla, Kimberly S. Canter, Lori Wiener, Victoria Sardi‐Brown, Julia B. Tager, Kamyar Arasteh, Anne E. Kazak   +8 more
wiley   +1 more source

Exercise Capacity, Physical Activity, Fatigue, and Neurocognitive Function in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess, Gustaf Glavå, Simon Skau, Hans‐Georg Kuhn, Maria Bäck, Marianne Jarfelt   +5 more
wiley   +1 more source

Comparison of clinical features and oncologic outcomes between familial non-hereditary and hereditary breast cancer in Korean female patients

Asian Journal of Surgery, 2020
Background: The authors compared the clinical features between familial (non-hereditary) and hereditary breast cancer. And we also analyzed their oncologic outcomes to establish appropriate surveillance protocol for familial (non-hereditary) and ...
Chan Sub Park, Ho Yong Park, Jin Hyang Jung, Wan Wook Kim, Yee Soo Chae, Soo Jung Lee, Ji-Young Park, Jee Young Park, Jeeyeon Lee   +8 more
doaj   +1 more source

“We Cannot Talk as a Family”: Complexities of Survivorship Communication Among Hispanic/Latino Young Adult Survivors of Childhood Cancer, Parents, and Clinicians

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Young adult childhood cancer survivors (YA‐CCS) have an increased risk of treatment‐related health complications throughout their lives. Lifelong survivorship care is recommended, yet many YA‐CCS experience disruptions in care during pediatric‐to‐adult transitions and do not receive recommended survivorship care.
Kevin Shanchen Pu, Nicole Fernández‐Viña, Briana C. Martin‐Villa, Daniela Ramirez, Rebecca M. Lewinsohn, Mary Smith, Heidi Boynton, Lidia Schapira, Stephanie M. Smith   +8 more
wiley   +1 more source

Comparative insight: hereditary colorectal cancer registries in Iran, Singapore, and South Africa

This study compares three hereditary colorectal cancer (CRC) registries—the Iranian Hereditary Colorectal Cancer Registry (IHCCR), the Singapore Polyposis Registry (SPR), and the University of Cape Town Familial CRC Registry—to illuminate diverse ...
Ngeow, Joanne, Manisekaran, Rutharra Ghayadthri, Caeser, Rebecca, Goshayeshi, Ladan, Goldberg, Paul, Li, Shao-Tzu, Monahan, Kevin J., Ramesar, Raj, Eu, Ernest Wencong, Tan, Yu Bin, Boutall, Adam, Goshayeshi, Lena, Algar, Ursula   +12 more
core   +1 more source

Classical Complement Pathway Inhibition in a Pediatric Patient With Refractory Immune Thrombocytopenia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric refractory immune thrombocytopenia (rITP) is generally characterized by persistent thrombocytopenia and failure to achieve a sustained response to multiple standard therapies. We report a 4‐year‐old female with congenital tufting enteropathy, post‐intestinal transplant patient on immunosuppressants, who developed severe rITP ...
Sarah Hsieh, Susmita Sarangi, Caileigh Pudela, Catherine M. Broome, Tara K. Suntum   +4 more
wiley   +1 more source

Addressing uncertainty in hereditary colorectal cancer: the role of a regional expert multidisciplinary team meeting.

There is frequent uncertainty in both the precise quantification of risk, and the application of clinical interventions, designed to mitigate increased heritable colorectal cancer (CRC) susceptibility.
Brady, Angela F, Latchford, Andrew, McVeigh, T, Cuthill, Vicky, DeSouza, Bianca, Monahan, Kevin J, DeSouza, B, Brady, AF, McVeigh, Terri, Latchford, A, Varde, A, Cuthill, V, Monahan, KJ, Varde, Avani   +13 more
core   +1 more source

Cancer trends: Breast, cervical and colorectal cancer 1994-2019: National trends for cancers with population-based screening programmes in Ireland

, 2022
The overall burden of cancer in Ireland is increasing, primarily due to population growth and ageing, with the annual number of cases of breast cancer, cervical cancer and colorectal cancer estimated to increase by 50%, 56% and 113% respectively by 2045 ...
National Cancer Registry Ireland (NCRI)
core  

Fruits, vegetables, and hMLH1 protein-deficient and -proficient colon cancer: The Netherlands cohort study. [PDF]

, 2005
BACKGROUND: Clinical and pathologic differences exist between colon carcinomas deficient and proficient in the mismatch repair protein hMLH1. Animal and in vitro studies suggest that fruits, vegetables, folate, and antioxidants are associated with ...
Brandt, P.A. van den, van Wijhe, G., van Muijen, Goos NP, Goldbohm, R.A., van Wijhe, Gerda, Goldbohm, R Alexandra, Muijen, G.N.P. van, van den Brandt, Piet A, Wijhe, G. van, Wark, Petra A.; id_orcid, Goldbohm, R. Alexandra, Van Muijen, Goos N P, Van Den Brandt, Piet A., Veer, P. van 't, van 't Veer, Pieter, Weijenberg, Matty P., Weijenberg, Matty P, de Goeij, Anton FPM, Wark, P.A., De Goeij, Anton F P M, van Muijen, G.N.P., van 't Veer, P., van den Brandt, P.A., Luchtenborg, M., Goeij, A.F.P.M. de, Goeij, A.F. de, Weijenberg, M.P., Wark, Petra A, Lüchtenborg, Margreet, de Goeij, A.F., de Goeij, A.F.P.M., Van't Veer, Pieter   +31 more
core   +3 more sources