Novel Development of a Large Cerebral Cavernous Malformation in an Adolescent With a History of Familial Cerebral Cavernous Malformation Syndrome. [PDF]
CureusCerebral cavernous malformations (CCM) are capillary vascular malformations of the central nervous system (CNS). These lesions can be either familial or sporadic. We present a case of a 16-year-old girl with familial CCM syndrome who presented with a six-
McIntosh MG, Hayes LL.
europepmc +4 more sources
Familial Cerebral Cavernous Malformation Mimicking Cerebral Amyloid Angiopathy. [PDF]
Neurol Clin Pract, 2021 A 67-year-old man was referred from ophthalmology for possible cerebral amyloid angiopathy (CAA) discovered during work-up of possible optic neuropathy.
Ridha M, Aziz Y, Broderick J.
europepmc +4 more sources
Natural history of familial cerebral cavernous malformation syndrome in children: a multicenter cohort study. [PDF]
Neuroradiology, 2023 Purpose There is limited data concerning neuroimaging findings and longitudinal evaluation of familial cerebral cavernous malformations (FCCM) in children.
Geraldo AF +15 more
europepmc +2 more sources
Familial Cerebral Cavernous Malformations : A Clinical Series and Literature Review. [PDF]
J Korean Neurosurg SocObjective Familial cerebral cavernous malformation (FCCM) is a genetically inherited condition involving the collection of abnormal slow-flow venous capillaries with no cerebral parenchyma in between.
Dogu H +5 more
europepmc +5 more sources
Two cases of familial cerebral cavernous malformation caused by mutations in the gene [PDF]
Korean Journal of Pediatrics, 2016 Cerebral cavernous malformation (CCM) is a vascular malformation characterized by abnormally enlarged capillary cavities without any intervening neural tissue.
Im-Yong Yang +5 more
doaj +2 more sources
Transient Dysphagia as a Presenting Symptom of Familial Cerebral Cavernous Malformation. [PDF]
CureusCerebral cavernous malformations (CCMs) are vascular lesions characterized by a collection of thin-walled capillaries with slow blood flow, which are often identified incidentally on MRI.
Scott ML, Ross DE.
europepmc +2 more sources
Familial cerebral cavernous malformation presenting with epilepsy caused by mutation in the CCM2 gene: A case report. [PDF]
Medicine (Baltimore), 2020 Rationale: Cerebral cavernous malformation (CCM) of the familial type is caused by abnormalities in the CCM1, CCM2, and CCM3 genes. These 3 proteins forming a complex associate with the maintenance of vascular endothelial cell-cell junctions. Dysfunction
Ishii K +4 more
europepmc +2 more sources
Asymptomatic Familial Multiple Cerebral Cavernous Malformation in a 73-Year-Old Woman
Case Reports in Radiology, 2021 Cerebral cavernous malformations (CCMs) are dilated blood vessels which can develop sporadically or in familial form and are the commonest malformations of blood vessels in the spinal cord and brain.
Klenam Dzefi-Tettey +4 more
doaj +2 more sources
Obstructive hydrocephalus secondary to an anterior mesencephalic cavernous malformation with familial cerebral cavernous malformation syndrome: A case report. [PDF]
Radiol Case RepCerebral Cavernous malformations (CCM) are the second most common vascular malformation of the central nervous system accounting (CNS) for 5%-10% of vascular malformations in the CNS with a prevalence of 0.5%.
Khalil G, Raad E, Khalil MA, Hay JA.
europepmc +2 more sources
The frameshift Leu220Phefs*2 variant in KRIT1 accounts for early acute bleeding in patients affected by cerebral cavernous malformation [PDF]
Interdisciplinary Neurosurgery, 2021 Background and Objectives: Cerebral cavernous malformation (CCM) is a neurovascular disease characterized by abnormally expanded and tortuous microvessels with increased predisposition to thrombosis and focal hemorrhage.
Autilia Tommasina Buonagura +8 more
doaj +3 more sources