Results 51 to 60 of about 3,068 (175)

Advances and Prospects of Stereotactic Radiosurgery and Stereotactic Ablative Body Radiotherapy: Evolving Paradigms in Precision Oncology

Med Research, EarlyView.
The graphical abstract outlines the progressive development and impact of stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT). Technological Evolution illustrates the transition from brachytherapy with single‐dose, LDR/HDR schedules to fractionated radiotherapy, three‐dimensional conformal radiotherapy (3DCRT) and Gamma Knife ...
Jing Zhang, Wenhao Xu, Weiqing Lu, Yingxuan Lin, Luoxi He, Zonglin Lv, Yiliyaer Nuerrula, Zouting, Zhen Zhang, Hailiang Zhang, Xuejun Ma   +10 more
wiley   +1 more source

Angioneogenese in cerebralen Arteriovernösen Malformationen [PDF]

, 2004
Arteriovenöse Malformationen werden in der Literatur meistens als angeborene und statische Gefäßmissbildungen beschrieben. Neuere Arbeiten und Erkenntnisse legen jedoch eine dynamische Biologie dieser Malformationen nahe.
Battenberg, Elmar, Sure, U. (PD Dr. med.)   +1 more
core   +1 more source

Vascularised Brain Organoids: Engineering Strategies and Neurobiological Applications

Cell Proliferation, EarlyView.
This review highlights emerging strategies to engineer vascularized brain organoids—including endothelial co‐culture, genetic induction, perfusion systems, and in vivo transplantation—and their applications in modelling neurovascular diseases, evaluating BBB drug delivery, and advancing regenerative medicine.
Yeajin Song, Hyejin Jo, Seokchan Jeong, Inseon Kim, Seunghun S. Lee   +4 more
wiley   +1 more source

Angioma cavernoso familiar: relato em três gerações Familial cavernous angioma: report in three generations

Arquivos de Neuro-Psiquiatria, 1996
O angioma cavernoso ou cavemoma é malformação vascular que acomete 0,5 a 0,7% da população, perfazendo 8 a 15% de todas as malformações vasculares do neuroeixo, sendo a segunda malformação mais frequente do sistema nervoso central.
Jean-Luc Fobe, João Batista Nogueira de Lima, Mauro Livio de Buone, Jordão Correa Neto   +3 more
doaj   +1 more source

Defective autophagy is a key feature of cerebral cavernous malformations

EMBO Molecular Medicine, 2015
Cerebral cavernous malformation (CCM) is a major cerebrovascular disease affecting approximately 0.3–0.5% of the population and is characterized by enlarged and leaky capillaries that predispose to seizures, focal neurological deficits, and fatal ...
Saverio Marchi, Mariangela Corricelli, Eliana Trapani, Luca Bravi, Alessandra Pittaro, Simona Delle Monache, Letizia Ferroni, Simone Patergnani, Sonia Missiroli, Luca Goitre, Lorenza Trabalzini, Alessandro Rimessi, Carlotta Giorgi, Barbara Zavan, Paola Cassoni, Elisabetta Dejana, Saverio Francesco Retta, Paolo Pinton   +17 more
doaj   +1 more source

Familiäre Kavernome des Zentralnervensystems: Eine klinische und genetische Studie an 15 deutsche Familien [PDF]

, 2018
Zusammenfassung: 1928 beschrieb Hugo Friedrich Kufs erstmalig eine Familie mit zerebralen, retinalen und kutanen Kavernomen. Mittlerweile wurden über 300 weitere Familien beschrieben.
Andermann, E., Andermann, F., Baumann, C., Bertalanffy, H., Dichgans, J., Elger, C., Hopf, H., Hopf, N., Keidel, M., Kleider, A., Nowak, G., Pfeiffer, R., Rouleau, G., Schramm, J., Siegel, A., Spuck, S., Stefan, H., Sure, U., Verlaan, D.   +18 more
core  

A novel CCM3 mutation associated with cerebral cavernous malformation in a Chinese family

Therapeutic Advances in Neurological Disorders, 2020
Background: Cerebral cavernous malformation (CCM), especially the familial form, is a relatively rare congenital and occult vascular disease of the central nervous system.
Xiao-yu Jiang, Ying Zhang, Xiang Yin, Di Nan, Xu Wang, Jia-chun Feng, Jing Miao   +6 more
doaj   +1 more source

Rates and characteristics of radiographically detected intracerebral cavernous malformations after cranial radiation therapy in pediatric cancer patients. [PDF]

, 2014
Rates and characteristics of intracerebral cavernous malformations after cranial radiation therapy remain poorly understood. Herein we report on intracerebral cavernous malformations detected on follow-up imaging in pediatric cancer patients who received
Chettout, Nassim, Cotter, Jennifer, Fullerton, Heather, Gastelum, Erica, Haas-Kogan, Daphne A, Hess, Christopher, Hills, Nancy, Mueller, Sabine, Randazzo, Dominica, Roddy, Erika, Sear, Katherine   +10 more
core   +2 more sources

Varying clinical presentations of familial cerebral cavernous malformations (CCMs) and spinal cord cavernous malformations (SCCMs)

Radiology Case Reports, 2012
We present a family afflicted by both extensive cerebral cavernous malformations (CCMs) and spinal cord cavernous malformations (SCCMs). These may be inherited in an autosomal dominant pattern or occur sporadically. The presentation varies and may include a multitude of clinical symptoms separated in time and space.
Nicholas-Bublick, Selena, Koffman, Boyd M.   +1 more
openaire   +2 more sources

Sensitivity of patients with familial cerebral cavernous malformations to therapeutic radiation [PDF]

Journal of Medical Imaging and Radiation Oncology, 2015
SummaryFamilial cerebral cavernous malformations are autosomal dominant conditions that can result in significant morbidity. A two‐hit mechanism is accepted as likely responsible for formation of these malformations. We present two patients with this disease who received therapeutic radiation and developed very high numbers of malformations within the ...
Michael, Golden, Saba, Saeidi, Benny, Liem, Eric, Marchand, Leslie, Morrison, Blaine, Hart   +5 more
openaire   +2 more sources